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Chemogenetic tools for causal cellular and neuronal biology
(American Physiological Society, 2018)
Chemogenetic technologies enable selective pharmacological control of specific cell populations. An increasing number of approaches have been developed that modulate different signaling pathways. Selective pharmacological ...
Focal therapy of prostate and kidney cancer
(Lippincott Williams & Wilkins, 2018)
We are delighted to present this special issue of ‘Current Opinion in Urology’ addressing several contemporary topics of focal therapy for prostate and kidney cancers. Over the past two decades, we have observed the changing ...
Prostate cancer multifocality, the index lesion, and the microenvironment
(Lippincott Williams & Wilkins, 2018)
Purpose of reviewMost of focal therapies has addressed index lesion as the targeted tumour focus to treat localized prostate cancer (PCa), a multifocal disease. The interaction between tumour foci and host cells creates a ...
Positioning Europe for the epitranscriptomics challenge
(Taylor and Francis Inc., 2018)
The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built. ...
Therapeutic role of rifampicin in Alzheimer's disease
(Wiley, 2018)
Rifampicin exerts significant brain protective functions in multiple experimental models. Here we summarize the underlying mechanisms of the neuroprotective and pro-cognitive effects of rifampicin that are mediated by its ...