Ara
Toplam kayıt 36, listelenen: 11-20
Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: A preliminary study
(Lippincott Williams & Wilkins, 2018)
Anti-leucine-rich glioma inactivated 1 (anti-LGI1) encephalitis is one of the most frequently encountered forms of autoimmune encephalitis. Many patients with anti-LGI1 encephalitis develop permanent hippocampal neuron ...
Time dependent impact of perinatal hypoxia on growth hormone, insulin-like growth factor 1 and insulin-like growth factor binding protein-3
(Springer/Plenum Publishers, 2016)
Hypoxic-ischemia (HI) is a widely used animal model to mimic the preterm or perinatal sublethal hypoxia, including hypoxic-ischemic encephalopathy. It causes diffuse neurodegeneration in the brain and results in mental ...
Bisphenol a and di(2-ethylhexyl) phthalate exert divergent effects on apoptosis and the Wnt/-catenin pathway in zebrafish embryos: A possible mechanism of endocrine disrupting chemical action
(Sage Publications Inc, 2017)
Polyethylene terephthalate (PET) and polycarbonate (PC) are the most commonly used plastics in water bottles. Di(2-ethylhexyl) phthalate (DEHP) is used as a plasticizer in PET plastics, and bisphenol A (BPA) is used to ...
Methylnitrosourea, dimethylbenzanthracene and benzoapyrene differentially affect redox pathways, apoptosis and immunity in zebrafish
(SAGE Publications Ltd, 2020)
Cancer continues to be a major cause of mortality globally. Zebrafish present suitable models for studying the mechanisms of genotoxic carcinogens. The aim of this study was to investigate the interaction between ...
Dose-dependent effects of vitamin 1,25(OH)2D3 on oxidative stress and apoptosis
(Walter de Gruyter GmbH, 2018)
The purpose of this study is to examine the dose-dependent effects of vitamin 1,25(OH)2D3 on apoptosis and oxidative stress. In this study, 50 male Balb/c mice were used as control and experiment groups. The mice were ...
Delayed therapeutic administration of melatonin enhances neuronal survival through AKT and MAPK signaling pathways following focal brain ischemia in mice
(Springer Nature, 2022)
Melatonin has a role in the cell survival signaling pathways as a candidate for secondary stroke prevention. Therefore, in the present study, the coordination of ipsilateral and contralateral hemispheres to evaluate delayed ...
Effects of gallic acid on endometrial cancer cells in two and three dimensional cell culture models
(Asian Pacific Organization for Cancer Prevention, 2021)
Background and Aim: Cell culture studies are an indispensable tools used to understand basic physiological, biophysical and biomolecular mechanisms. Although traditional two-dimensional (2D) cell culture models are more ...
Biochemical and proteomic analysis of a potential anticancer agent: Palladium(II) saccharinate complex of terpyridine acting through double strand break formation
(American Chemical Society, 2014)
Metal based chemotherapeutic drugs are widely used as an effective method to defeat various cancers. In this study, the mechanism of action of a novel therapeutic agent, [Pd(sac)(terpy)](sac)center dot 4H(2)O (sac = ...
Antiproliferative and apoptotic effects of onobrychis albiflora extract on HCT-116 cells
(Ondokuz Mayıs University, 2018)
In this study, the cytotoxic effects of the extracts of methanol: water (80:20) prepared from the above-ground parts of the varieties of Onobrychis albiflora Hub.-Mor., Onobrychis argyrea Boiss. subsp. argyrea, Onobrychis ...
The effect of kisspeptin on spermatogenesis and apoptosis in rats
(TUBITAK Scıentıfıc & Technical Research Council Turkey, 2017)
Background/aim: To study the effect of kisspeptin, a gonadotropin release stimulator, on the testicular tissue of the rat. Materials and methods: Four groups were formed as follows: control, Kiss-10 50 nmol administration ...