Bölüm "İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı" Makale Koleksiyonu için listeleme
Toplam kayıt 67, listelenen: 1-20
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ABCG5 and ABCG8 gene polymorphisms in type 2 diabetes mellitus in the Turkish population
(Elsevier, 2015)Objective: The aim of the present study was to investigate the relationship between ABCG5 and ABCG8 gene polymorphisms and plasma lipid concentrations in Turkish patients with type 2 diabetes mellitus. Methods: Included ... -
Active shrinkage protects neurons following axonal transection
(Elsevier Inc., 2023)Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ... -
Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
(Frontiers Media Sa, 2019)Repetitive transcranial magnetic stimulation (rTMS) has gained interest as a non-invasive treatment for stroke based on the data promoting its effects on functional recovery. However, the exact action mechanisms by which ... -
Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
(Elsevier B.V., 2022)Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ... -
Antioxidant activity and anti-cancer effects of bilberry (vaccinium myrtillus l.) fruit extract on gastric cancer, ags cell line
(Ankara University, 2022)Objective: Vaccinium myrtillus L. fruits are consumed as food. This research was aimed to evaluate V. myrtillus methanol extract antioxidant and cytotoxic activities and determine its anti-cancer potential to further study ... -
Antioxidant activity of blackthorn (Prunus spinosa L.) fruit extract and cytotoxic effects on various cancer cell lines
(Logos Medical Publishing, 2019)Objective: Blackthorn (Prunus spinosa L. (Rosaceae) is a shrup whose fruits are consumed as food in Turkey. This study was aimed to evaluate antioxidant activity of methanol extract of P. spinosa and its cytotoxic effects ... -
Arctium minus metanol ekstresinin çeşitli kanser hücre hatları üzerinde sitotoksik etkileri
(Ankara Üniversitesi, 2022)Amaç: Bu çalışmada Arctium minus (Hill) Bernh. ssp. minus’un toprak üstü kısımlarından elde edilen metanol ekstresinin kanser hücre hatları üzerindeki sitotoksik etkilerinin değerlendirilmesi amaçlanmıştır. Gereç ve ... -
Axolotl cells and tissues enhances cutaneous wound healing in mice
(2016)Adult mammalian skin wound repair is defective due to loss of the regulation in balancing the complete epithelial regeneration and excessive connective tissue production, and this repair process commonly results in scar ... -
Cardiac immunology: A new era for immune cells in the heart
(Plenum Press, 2021)The immune system is essential for the development and homeostasis of the human body. Our current understanding of the immune system on disease pathogenesis has drastically expanded over the last decade with the definition ... -
Cytokine gene polymorphism frequencies in Turkish population living in Marmara region
(De Gruyter Open Ltd, 2022)Objectives Sequence variants in cytokine genes are related to affect cytokine gene levels. In this study, it was aimed to examine eight single nucleotide polymorphisms (SNPs) in five cytokine genes (TNF-alpha, INF-gamma, ... -
Defining optimal enzyme and matrix combination for replating of human induced pluripotent stem cell-derived cardiomyocytes at different levels of maturity
(Elsevier Inc., 2021)Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational research. Depending on the maturity of cardiac cultures and the intended applications, ... -
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines
(Elsevier Inc., 2022)Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of ... -
Design of IKVAV peptide/gold nanoparticle decorated, micro/nano-channeled PCL/PLGA film scaffolds for neuronal differentiation and neurite outgrowth
(Elsevier Ltd, 2023)In the field of neural tissue engineering, intensive efforts are being made to develop tissue scaffolds that can support an effective functional recovery and neural development by guiding damaged axons and neurites. ... -
Determination of burnout and job satisfaction levels in nurses working in the surgical clinics
(2019)Objective: The aim of this study was to assess the effect of sociodemographic and professional characteristics of nurses working in thesurgical services on their burnout and job satisfaction levels.Method: The study was ... -
Development of BDNF/NGF/IKVAV peptide modified and gold nanoparticle conductive PCL/PLGA nerve guidance conduit for regeneration of the rat spinal cord injury
(2024)Spinal cord injuries are very common worldwide, leading to permanent nerve function loss with devastating effects in the affected patients. The challenges and inadequate results in the current clinical treatments are leading ... -
Dose-dependent neuroprotective effect of enoxaparin on cold-induced traumatic brain injury
(Medknow Publications & Media Pvt Ltd., 2017)Recent evidence exists that enoxaparin can reduce brain injury because of its anticoagulant activity. To investigate the potential therapeutic effect of enoxaparin on cold-induced traumatic brain injury, at 20 minutes after ... -
DU 145 insan prostat kanseri hücrelerinde Hsa-Mir-8072’nin potansiyel rolü
(Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2019)Amaç: Çalışmamızda, insan prostat kanser hücre hattı (DU145) ve prostat normal epitel hücre hatları (RWPE) arasında miRNA ifadesinin analizini yapmak ve kanser gelişiminde olası rolünü incelemeği amaçladık. Gereçler ve ... -
The effect of systemic rifampicin treatment on inferior alveolar nerve regeneration in rats following crush injury
(Wiley, 2020)Axonal regeneration of the inferior alveolar nerve (IAN) is a therapeutic target for functional recovery after peripheral nerve injury. Rifampicin exerts anti-apoptotic, anti-inflammatory, and anti-oxidant effects on nerve ... -
The effect of ultrasound-guided serratus plane block on the quality of life in patients undergoing modified radical mastectomy and axillary lymph node dissection: A randomized controlled study
(NLM (Medline), 2022)BACKGROUND: Modified radical mastectomy (MRM) and axillary lymph node dissection (AD) are the most commonly used surgical methods in breast cancer surgery, and they are characterized by moderate to severe pain. This study ... -
Effects of foeniculum vulgare essential oil compounds, fenchone and limonene, on experimental wound healing
(Taylor and Francis Ltd, 2017)We investigated the wound healing efficacy of the Foeniculum vulgare compounds, fenchone and limonene, using an excisional cutaneous wound model in rats. An excision wound was made on the back of the rat and fenchone and ...