ORCID "0000-0002-3412-0807" Makale Koleksiyonu için listeleme
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An alternative approach wound healing field with polypodium vulgare
Batur, Şebnem; Ayla, Şule; Şakul, Ayşe Arzu; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Özdemir, Ekrem Musa; Kepil, Nuray; Günal, Mehmet Yalçın (Logos Medical Publishing, 2020)Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ... -
Anti-inflammatory, analgesic and in vivo-in vitro wound healing potential of the Phlomis rigida Labill. extract
Okur, Mehmet Evren; Karadağ, Ayşe Esra; Özhan, Yağmur; Sipahi, Hande; Ayla, Şule; Daylan, Benay; Kültür, Şükran; Demirci, Betül; Demirci, Fatih (Elsevier Ireland Ltd, 2021)Ethnopharmacological relevance: The preparations of Phlomis aerial parts are used traditionally in Anatolia for wound healing and in inflammatory disorders. Methods: For the identification of the active fraction, the air ... -
Antioxidant activity and anti-cancer effects of bilberry (vaccinium myrtillus l.) fruit extract on gastric cancer, ags cell line
Karakaş, Nihal; Okur, Mehmet Evren; Sağır, Tuğba; Uludağ, Damla; Polat, Derya Çiçek; Karadağ, Ayşe Esra (Ankara University, 2022)Objective: Vaccinium myrtillus L. fruits are consumed as food. This research was aimed to evaluate V. myrtillus methanol extract antioxidant and cytotoxic activities and determine its anti-cancer potential to further study ... -
Antioxidant activity of blackthorn (Prunus spinosa L.) fruit extract and cytotoxic effects on various cancer cell lines
Karakaş, Nihal; Okur, Mehmet Evren; Öztürk, İrem; Ayla, Şule; Karadağ, Ayşe Esra; Polat, Derya Çiçek (Logos Medical Publishing, 2019)Objective: Blackthorn (Prunus spinosa L. (Rosaceae) is a shrup whose fruits are consumed as food in Turkey. This study was aimed to evaluate antioxidant activity of methanol extract of P. spinosa and its cytotoxic effects ... -
Arctium minus metanol ekstresinin çeşitli kanser hücre hatları üzerinde sitotoksik etkileri
Sayın Şakul, Ayşe Arzu; Yozgat Byrne, Yasemin; Karadağ, Ayşe Esra; Altınalan, Ebrar; Çimen, Şeyma; Okur, Mehmet Evren (Ankara Üniversitesi, 2022)Amaç: Bu çalışmada Arctium minus (Hill) Bernh. ssp. minus’un toprak üstü kısımlarından elde edilen metanol ekstresinin kanser hücre hatları üzerindeki sitotoksik etkilerinin değerlendirilmesi amaçlanmıştır. Gereç ve ... -
Comparative in vitro and in silico enzyme inhibitory screening of rosa x damascena and pelargonium graveolens essential oils and geraniol
Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Demirci, Betül; Demirci, Fatih; Ghani, Usman (Multidisciplinary Digital Publishing Institute (MDPI), 2023)The present work aims to evaluate Rosa x damascena Herrm. and Pelargonium graveolens L’Hér. essential oils, and the major constituent geraniol for their in vitro and in silico inhibitory activities against 5-lipoxygenase ... -
Evaluation of in vitro anti-cancer effects of Styphnolobium japonicum root extract in human colon (HT-9), brain (U-87), and prostate (PC-3) cancer cell lines
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Öztunç, Nurşah; Tosyalı, İbrahim Serkut; Demirci, Fatih (İstanbul University, 2020)Background and Aims: Styphnolobium japonicum (L.) Schott. (Sophora japonica) is a medicinal plant applied for various diseases, in the traditional medicine field. The evaluation of methanol extract of S. japonicum root ... -
In vitro cytotoxicity evaluation of Marrubium vulgare L. methanol extract
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Yılmaz, Rabia; Demirci, Fatih (Marmara University, 2019)Marrubium vulgare L. (Lamiaceae) is a herbal drug used for centuries for many diseases. In this present study the plant material was acquired from commercial sources in pharma grade (PhEur 8.0) quality. The methanol extract ... -
In vivo wound healing and in vitro anti-inflammatory activity evaluation of phlomis russeliana extract gel formulations
Okur, Mehmet Evren; Karadağ, Ayşe Esra; Üstündağ Okur, Neslihan; Özhan, Yağmur; Sipahi, Hande; Ayla, Şule; Daylan, Benay; Demirci, Betül; Demirci, Fatih (MDPI, 2020)The air-dried aerial parts of Phlomis russeliana (Sims) Lag. Ex Benth. was extracted by methanol and fractionated by n-hexane, dichloromethane, and ethyl acetate, respectively. The wound healing properties of P. russeliana ... -
In vivo wound-healing and in vitro antibacterial and antioxidant of Carduus extract
Şakul, Ayşe Arzu; Ayla, Şule; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Güzel, Elif; Özdemir, Ekrem Musa; Günal, Mehmet Yalçın (Marmara University, 2023)Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Turkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ... -
In vivo wound-healing and in vitro antibacterial and antioxidant properties of Carduus adpressus extract
Şakul, Ayşe Arzu; Ayla, Şule; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Güzel, Elif; Özdemir, Ekrem Musa; Günal, Mehmet Yalçın (Marmara University, 2023)Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Türkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ... -
Investigation of antioxidant and cytotoxic activities of Opuntia ficus-indica (L.) Mill. fruit extract
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Uludağ, Damla; Çiçek Polat, Derya (Istanbul University, 2019)Opuntia ficus-indica fruits are claimed to possess several health-beneficial properties. This study was carried out to determine the phytochemicals as well as to compare antioxidant activity and cell viability of the ... -
Laurocerasus officinalis Roem. fruit extract induces cell death through caspase mediated apoptosis in gastric cancer cell lines
Karakaş, Nihal; Okur, Mehmet Evren; Öztunç, Nurşah; Polat, Derya Çiçek; Karadağ, Ayşe Esra (Walter de Gruyter GmbH, 2021)Objectives: Laurocerasus officinalis Roem. fruits are traditionally used for several health problems. Although there are some studies about its antiproliferative effects on different cancer cells, no study was reported ... -
A novel approach in the treatment of osteoarthritis: In vitro and in vivo evaluation of Allium sativum microemulsion
Okur, Mehmet Evren; Kolbaşı, Bircan; Şahin, Mustafa; Karadağ, Ayşe Esra; Reis, Rengin; Çağlar, Emre Şefik; Kaplan, Arife Ahsen; Sipahi, Hande; Keskin, İlknur; Demiralp, Bahtiyar; Üstündağ Okur, Neslihan (Wiley, 2022)Osteoarthritis (OA) is the most prevalent kind of joint disease, affecting millions of individuals worldwide. Allium sativum L. was used as a therapeutic agent in the microemulsion system against osteoarthritis due to ... -
Opuntia ficus indica fruits ameliorate cisplatin-induced nephrotoxicity in mice
Okur, Mehmet Evren; Ayla, Şule; Karadağ, Ayşe Esra; Polat, Derya Çiçek; Demirci, Sibel; Seçkin, İsmail (Pharmaceutical Society of Japan, 2020)This study aims to determine the potential renal protective effects of Opuntia ficus-indica (L.) Miller (OFI) fruits against cisplatin-induced nephrotoxicity in mice. The antioxidant activity of OH methanol extract was ... -
Tilia tomentosa moench çiçeklerinin uçucu bileşenlerinin ve çeşitli in vitro biyolojik aktivitelerinin incelenmesi
Karakaş, Nihal; Okur, Mehmet Evren; Öztunç, Nurşah; Karadağ, Ayşe Esra; Kültür, Şükran; Demirci, Betül (2019)Amaç: Tilia tomentosa Moench. (Malvaceae) bitkisinin çiçeklerinden elde edilen n-hekzan ekstresinin uçucu bileşenleri, toplam fenolik madde miktarı, in vitro antioksidan, antimikrobiyal ve hücre canlılığı aktivitelerinin ... -
Wound healing activity of arum maculatum
Arzu Şakul, Ayşe; Okur, Mehmet Evren; Ayla, Şule; Daylan, Benay; Karadağ, Ayşe Esra; Batur, Şebnem; Özdemir, Ekrem Musa; Altınalan, Ebrar; Günal, Mehmet Yalçın (Istanbul Medeniyet University, 2023)Objective: In this study, the antioxidant properties of Arum maculatum plant were evaluated. This study reported for the first time the wound healing activity of the methanol extract of A. maculatum fruits. This study aimed ... -
Wound healing effect of naringin gel in alloxan induced diabetic mice
Okur, Mehmet Evren; Şakul, Ayşe Arzu; Ayla, Şule; Karadağ, Ayşe Esra; Şahin Şenyüz, Cemre; Batur, Şebnem; Daylan, Benay; Özdemir, Ekrem Musa; Palabıyık-Yücelik, Sezin; Sipahi, Hande; Aydın, Ahmet (Ankara University Faculty of Pharmac, 2020)Objective: The aim of this study was to investigate the effects of naringin, a known flavonoid, on in vitro cytotoxicity, irritation and in vivo potential efficacy when topically applied to the diabetic wound. Material and ...