ORCID "0000-0001-6830-7701" Makale Koleksiyonu için listeleme
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Calculation of the Ki67 index in pancreatic neuroendocrine tumors: A comparative analysis of four counting methodologies
Reid, Michelle Dian; Bağcı, Pelin; Ohike, Nobuyuki; Saka, Burcu; Erbarut Seven, İpek; Dursun, Nevra; Balcı, Serdar; Gucer, Hasan; Jang, Kee-Taek; Tajiri, Takuma; Baştürk, Olca; Kong, So Yeon; Goodman, Michael; Akkaş, Gizem; Adsay, Volkan (Nature Publishing Group, 2015)Ki67 index is now an essential part of classification of pancreatic neuroendocrine tumors. However, its adaptation into daily practice has been fraught with challenges related to counting methodology. In this study, three ... -
Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1 alpha, CXCR4 and CA9 in colorectal carcinoma
Saka, Burcu; Ekinci, Özgür; Dursun, Ayşe; Akyürek, Nalan (Elsevier Gmbh, 2017)Objective: To investigate the immunohistochemical expressions of HIF-1 alpha, CA9 and CXCR4 in resected human CRC specimens in relation to clinicopathologic and prognostic variables. Methods: A total of 186 patients (mean(SD) ... -
Comparison of CT methods for determining graft steatosis in living donor liver transplantation
Şeker, Mehmet; Erol, Cengiz; Sevmiş, Şinasi; Saka, Burcu; Durur-Karakaya, Afak (Springer, 2019)Purpose: To evaluate and compare the diagnostic performance of non-enhanced computed tomography (NECT) and contrast-enhanced CT (CECT) attenuation indices in the assessment of hepatic steatosis by using biopsy as the ... -
The contribution of additional sampling in cholecystectomy materials: A multicenter prospective study
Abdullazade, Samir; Akarca, Fahire Göknur; Esendağlı, Güldal; Turhan, Nesrin; Erden, Esra; Savaş, Berna; Markoç, Fatma; Tuncel, Deniz; Özgüven Yılmaz, Banu; Saka, Burcu; Hallaç Keser, Sevinç; Şengiz Erhan, Selma; Gücin, Zühal; Sağol, Özgül; Ağalar, Anıl Aysal; Çelik, Sevinç; Özer, Hatice; Erbarut Seven, İpek; Ataizi Çelikel, Çiğdem; Ekinci, Özgür; Eğilmez, Hatice Reyhan; Balcı, Serdar; Akyol, Gülen (Federation of Turkish Pathology Societies, 2020)Objective: Cholecystectomy materials arc frequently encountered in routine practice. The aim of this study was to determine the true frequency of gallbladder lesions, the diagnostic consistency, and standardization of ... -
The conversion ofRASstatus in metastatic colorectal cancer patients after first-line biological agent treatment
Arıcı, Serdar; Hamdard, Jamshid; Sakin, Abdullah; Şengiz Erhan, Selma; Atçı, Muhammed Mustafa; Cekin, Ruhper; Saka, Burcu; Köse, Emin; Saydam, Tuba; Geredeli, Çağlayan; Cihan, Şener; Bilici, Ahmet (Wiley, 2021)Aim The aim was to investigate theRASdiscordance between initial and recurrent metastasectomy specimens in metastatic colorectal cancer (mCRC) patients treated with chemotherapy (CT) plus biological agents in a first-line ... -
The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats
Özdenkaya, Yaşar; Ölmüşçelik, Oktay; Basım, Pelin; Saka, Burcu; Arslan, Naciye Çiğdem (Ociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia, 2019)Purpose: To evaluate the effect of fibrin glue on staple-line leak after sleeve gastrectomy. Methods: Fourteen adult wistar rats 300 gr were randomized into two groups: Control group (n=7) and study group (n=7). All the ... -
Follicular cholecystitis: Reappraisal of incidence, definition, and clinicopathologic associations in an analysis of 2550 cholecystectomies
Saka, Burcu; Memiş, Bahar; Erbarut Seven, İpek; Pehlivanoğlu, Burçin; Balcı, Serdar; Bağcı, Pelin; Reid, Michelle; Dursun, Nevra; Tapia Escalano, Oscar; Carlos Roa, Juan; Carlos Araya, Juan; Kong, So Yeon; Baştürk, Olca; Koshiol, Jill; Adsay, N. Volkan (SAGE Publications Inc, 2020)Context.Follicular cholecystitis (FC) is a poorly characterized entity.Objective.To determine its frequency/clinicopathologic associations.Design.A total of 2550 cholecystectomy specimens were examined. Two hundred three ... -
Gallbladder polyps: Correlation of size and clinicopathologic characteristics based on updated definitions
Taşkın, Orhun C.; Baştürk, Olca; Reid, Michelle D.; Dursun, Nevra; Bağcı, Pelin; Saka, Burcu; Balcı, Serdar; Memiş, Bahar; Bellolio, Enrique; Araya, Juan Carlos; Roa, Juan Carlos; Tapia, Oscar; Losada, Hector; Sarmiento, Juan; Jang, Kee-Taek; Jang, Jin-Young; Pehlivanoğlu, Burçin; Erkan, Mert; Adsay, Volkan (Public Library of Science, 2020)Background Different perspectives exist regarding the clinicopathologic characteristics, biology and management of gallbladder polyps. Size is often used as the surrogate evidence of polyp behavior and size of >= 1cm is ... -
Hepatocellular carcinomas with granulomatous inflammation in tumor stroma: Clinicopathologic characteristics
Saka, Burcu; Özden, Ferhat; Armutlu, Ayşe; Ertuğrul, Gökhan (Federation of Turkish Pathology Societies, 2022)Objective: To determine the frequency of granulomatous inflammation within hepatocellular carcinoma (HCC) and its clinicopathologic associations. Material and Method: Fifty-eight HCCs (51 explants, 3 lobectomies, and 4 ... -
Karaciğer yağlanma oranı tespitinde dijital patolojinin katkısı
Amaç: Yağlanma oranı, steatohepatit tanısında ve transplantasyon öncesi verici adayı karaciğer biyopsilerinde değerlendirilmesi gereken parametrelerdendir. Kantitatif/semikantitatif olarak değerlendirilen yağlanma yüzdeleri, ... -
Non-neoplastic polyps of the gallbladder: A clinicopathologic analysis of 447 cases
Taşkın, Orhun; Bellolio, Enrique; Dursun, Nevra; Erbarut Seven, İpek; Roa, Juan C.; Araya, Juan C.; Villaseca, Miguel; Tapia, Oscar; Vance, Courtney; Saka, Burcu; Balcı, Serdar; Bağcı, Pelin; Losada, Hector; Sarmiento, Juan; Memis, Bahar; Pehlivanoğlu, Burçin; Baştürk, Olca; Reid, Michelle D.; Koshiol, Jill; Cheng, Jeanette; Kapran, Yersu; Adsay, Volkan (2020)There is no systematic histopathologic analysis of non-neoplastic polyps in the gallbladder. In this study, in addition to a computer search for cases designated as "polyp," a systematic review of 2533 consecutive routinely ... -
Pancreatic ductal adenocarcinoma is spread to the peripancreatic soft tissue in the majority of resected cases, rendering the AJCC T-stage protocol (7th Edition) inapplicable and Insignificant: A size-based staging system (pT1: ?2, pT2: >2–?4, pT3: >4 cm) is more valid and clinically relevant
Saka, Burcu; Balcı, Serdar; Baştürk, Olca; Bağcı, Pelin; Postlewait, Lauren Mc Lendon; Maithel, Shishir Kumar; Knight, Jessica; El Rayes, Bassel; Kooby, David; Sarmiento, Juan Martinez; Muraki, Takashi; Oliva, Irma; Bandyopadhyay, Sudeshna; Akkaş, Gizem; Goodman, Michael; Reid, Michelle Dian; Krasinskas, Alyssa; Everett, Rhonda; Adsay, Nazmi Volkan (Springer New York LLC, 2016)Background: Most studies have failed to identify any prognostic value of the current T-stage protocol for pancreatic ductal adenocarcinoma (PDAC) by the American Joint Committee on Cancer and the Union for International ... -
Poorly cohesive cell (diffuse-infiltrative/signet ring cell) carcinomas of the gallbladder: Clinicopathological analysis of 24 cases identified in 628 gallbladder carcinomas
Tuncel, Deniz; Carlos Roa, Juan; Carlos Araya, Juan; Bellolio, Enrique; Villaseca, Miguel; Tapia, Oscar; Jang, Kee-Taek; Quigley, Brian; Saka, Burcu; Baştürk, Olca; Sarmiento, Juan; Losada, Hector F.; Patel, Samip; Reid, Michelle D.; Memiş, Bahar; Adsay, Volkan (W B Saunders Co-Elsevier Inc, 2017)Signet ring cell carcinoma is an extremely rare type of gallbladder carcinoma: In the gastrointestinal system, carcinomas with single-cell or cord-like infiltration, previously called "diffuse-infiltrative" type or "signet ... -
The potential prognostic role of peritumoral eosinophils within whole tumor-associated inflammatory cells and stromal histological characteristics in colorectal cancer
Ramadan, Saime; Saka, Burcu; Yarıkkaya, Enver; Bilici, Ahmet; Öncel, Mustafa (Vesalius University Medical Publisher, 2020)We aimed to determine the prognostic role of whole tumor-associated inflammatory cells, especially eosinophils, and stromal histological characteristics in relation to other prognostic parameters in patients with colorectal ... -
Should be remembered in the differential diagnosis of klatskin Tumour: Alveolar echinococcosis
Saka, Burcu; Ünlü Akhan, Aslı; Erol, Cengiz; İstanbullu Tosun, Ayşe; Ertuǧrul, Gökhan (NLM (Medline), 2020)Alveolar echinococcosis is an infectious disease caused by Echinococcus multilocularis and it is frequently diagnosed as a space-occupying lesion in the liver. The growth pattern may be similar to that of a malignant tumour ... -
Substaging nodal status in ampullary carcinomas has significant prognostic value: Proposed revised staging based on an analysis of 313 well-characterized cases
Balcı, Serdar; Baştürk, Olca; Saka, Burcu; Bağcı, Pelin; Postlewait, Lauren Mc Lendon; Tajiri, Takuma; Jang, Kee-taek; Ohike, Nobuyuki; Kim, Grace Eun Hye; Krasinskas, Alyssa; Choi, Hyejeong; Sarmiento, Juan Martinez; Kooby, David; El-Rayes, Bassel; Knight, Jessica; Goodman, Michael; Akkaş, Gizem; Reid, Michelle Dian; Maithel, Shishir Kumar; Adsay, Nazmi Volkan (Society of Surgical Oncology, 2015)Background: Current nodal staging (N-staging) of ampullary carcinoma in the TNM staging system distinguishes between node-negative (N0) and node-positive (N1) disease but does not consider the metastatic lymph node (LN) ... -
Substaging of lymph node status in resected pancreatic ductal adenocarcinoma has strong prognostic correlations: Proposal for a revised N classification for TNM staging
Baştürk, Olca; Saka, Burcu; Balcı, Serdar; Postlewait, Lauren Mc Lendon; Knight, Jessica; Goodman, Michael; Kooby, David; Sarmiento J.M.; El-Rayes, Bassel; Choi, Hyejeong; Bağcı, Pelin; Krasinskas, Alyssa; Quigley, Brian Christopher; Reid, Michelle Dian; Akkaş, Gizem; Maithel, Shishir Kumar; Adsay, Nazmi Volkan (Springer, 2015)Background: The current tumor-node-metastasis staging system for the pancreas does not incorporate the number of lymph nodes (LNs) with metastasis. Methods: Among 1649 pancreaticoduodenectomies, 227 stringently defined ...