Başlık için Makale Koleksiyonu listeleme
Toplam kayıt 3651, listelenen: 1824-1843
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The IL-25/ILC2 axis promotes lung cancer with a concomitant accumulation of immune-suppressive cells in tumors in humans and mice
(Frontiers Media SA, 2023)Background: Group 2 innate lymphoid cells (ILC2) can be activated by interleukin (IL)-33 or IL-25. IL-25-activated ILC2 cells help protect the host against helminth infection while exacerbating allergic-like inflammation ... -
IL13 fused pseudomonas exotoxin targets various cancers in vitro
(International Institute of Anticancer Research, 2021)Background/Aim: Pseudomonas exotoxin (PE) is one of the most widely used toxins in the construction of therapeutic fusion proteins in pre-clinical studies followed by phase trials. In principle, PE acts by blocking protein ... -
IL13R alpha 2-and EGFR-targeted pseudomonas exotoxin potentiates the TRAIL-mediated death of GBM cells
(Spandidos Publications Ltd, 2021)Glioblastomas (GBMs) are refractory to current treatments and novel therapeutic approaches need to be explored. Pro-apoptotic tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is tumor-specific and has been ... -
Iliac artery perforation and treatment during lumbar disc surgery by simple balloon tamponade
(Springer, 2013)Introduction Although vascular injury during lumbar disc surgery is quite rare, it may be life threatening if not recognized and treated immediately. Case We report the case of a woman who had a left common iliac artery ... -
Imaging features to predict response to olfactory training in post-traumatic olfactory dysfunction
(John Wiley and Sons Inc, 2021)Objectives/Hypothesis: Prognosis of post-traumatic olfactory dysfunction is poor, with medical treatment options showing limited success rates. Olfactory training (OT) has been introduced as a potential therapeutic option ... -
Imaging findings of hepatosplenic schistosomiasis: A case report
(Elsevier Inc, 2016)In our study, in a 52-year-old man, specific and nonspecific findings of Schistosoma infestation were examined using ultrasonography, computed tomography, and magnetic resonance imaging. On computed tomography, capsular ... -
Imaging Granzyme B activity assesses immune-mediated myocarditis
(Lippincott Williams and Wilkins, 2015)Rationale: The development of molecular imaging approaches that assess specific immunopathologic mechanisms can advance the study of myocarditis. Objective: This study validates a novel molecular imaging tool that enables ... -
Imerslund-Grasbeck sendromu ve erken adolesans döneminde osteoporoz başlangıcı
(2012)İmerslund-Grasbeck sendromu (İGS), vitamin B12 eksikliği ve proteinüri ile seyreden iyi prognozlu bir malabsorpsiyon sendromudur. İleri yaşlarda bu hastalarda osteoporoz gelişimi önemli bir sorundur. Bu makalede, kliniğimizde ... -
Immature event-related alpha dynamics in children compared with the young adults during inhibition shown by day-night stroop task
(Frontiers Media SA, 2023)Introduction: Inhibitory control develops gradually from infancy to childhood and improves further during adolescence as the brain matures. Related previous studies showed the indispensable role of task-related alpha power ... -
Immune reconstitution inflammatory syndrome after hematopoietic stem cell transplantation in a FOXN1-deficient patient
(Lippincott Williams and Wilkins, 2023)The FOXN1 gene mutation is a unique disorder that causes the nude severe combined immunodeficiency phenotype. In patients with severe combined immunodeficiency, hematopoietic stem cell transplantation (HSCT) is life-saving ... -
Immunocytoexpression profile of ProExC in smears interpreted as ASC-US, ASC-H, and cervical intraepithelial lesion
(Medknow Publications & Media Pvt Ltd, 2017)Aims: We aimed to investigate the immunocytoexpression profiles of a novel assay ProEx C for topoisomerase II alpha (TOP2A) and minichromosome maintenance protein 2 (MCM2) in abnormal interpreted smears. Settings and Design: ... -
Immunoglobulin G4-related lung disease presenting with a mediastinal mass
(Turkiye Klinikleri Publisher, 2022)Immunoglobulin G4-related disease (IgG4-RD) is a recently identified systemic disease characterized by increased IgG4 level in serum and plasma cell infiltration resulting in “storiform fibrosis”. Although lung involvement ... -
Immunohistochemical expression profiles of MUC1 and MUC2 mucins in urothelial tumors of bladder
(Wolters Kluwer Medknow Publications, 2018)Background: Mucins may show aberrant expression, localization, and/or glycosylation in multiple malignancies. However, information regarding expression of these mucins is mostly unknown in urothelial tumors. Aim: This study ... -
Immunomodulator effect of topical zinc oxide application in tuberculin skin test
(Kare Publisher, 2018)OBJECTIVE: We aimed to evaluate the sensitivity of tuberculin skintest (purified protein derivative-PPD) by topical zinc application on test site to improve diagnostic reliability. METHODS: We performed this study in 100 ... -
The immunostimulatory effect of lactic acid bacteria in a rat model
(Shiraz Inst Cancer Res, 2016)Background: Probiotics are "live", beneficial microbes that provide important health benefits in their hosts. There is significant interest in the modulation and regulation of the immune function by probiotics. Objective: ... -
Impact of adding pertuzumab to trastuzumab plus chemotherapy in neoadjuvant treatment of HER2 positive breast cancer patients: A multicenter real-life HER2PATH study
(Taylor & Francis Ltd, 2023)AimTo investigate the pathological complete response (pCR) achieved after neoadjuvant therapy with versus without adding pertuzumab (P) to trastuzumab (H) plus neoadjuvant chemotherapy (NCT) in HER2+ breast cancer (BC) ... -
Impact of adjuvant gemcitabine containing chemotherapy following radical nephroureterectomy for patients with upper tract urothelial carcinoma: Results from a propensity-score matched cohort study
(IOS Press BV, 2023)BACKGROUND: The evidence regarding perioperative adjuvant chemotherapy and personalized surveillance strategies for upper tract urothelial carcinoma is limited. OBJECTIVE: To evaluate whether adjuvant gemcitabine ... -
Impact of allyl disulfide on oxidative damage and liver regeneration in an experimental hepatectomy model
(Editura Celsius, 2015)Backgraund: We investigated the effects of allyl disulfide (a garlic extract) on tissue damage, regeneration, proliferation and oxidative damage in an experimental liver resection model. Materials and Methods: In the study, ... -
Impact of antioxidant therapy on natural pregnancy outcomes and semen parameters in infertile men: A systematic review and meta-analysis of randomized controlled trials
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Seminal oxidative stress (OS) is a recognized factor potentially associated with male infertility, but the efficacy of antioxidant (AOX) therapy is controversial and there is no consensus on its utility. Primary ... -
Impact of aortic stiffness on the frequency of paroxysmal atrial fibrillation recurrences
(Taylor & Francis, 2015)Background The relationship between arterial stiff ness (AS) and atrial fi brillation (AF) incidence is well-known. In this study we aimed to investigate the relationship between AS parameters and AF occurence as well as ...
