ORCID "0000-0002-7059-1884" Makale Koleksiyonu için listeleme
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The effects of tacrolimus on the activity and expression of tissue factor in the rat ovary with ischemia-reperfusion induced injury
Üstündağ, Ünsal Veli; Şahin, Sadık; Ak, Koray; Keskin, İlknur; Emekli Alturfan, Ebru (Institute of Animal Reproduction and Food Research, 2015)In the present study, the effects of tacrolimus on the activity and expression of tissue factor (TF) were investigated in the ovarian ischemia-reperfusion induced injury in rats. Twenty-eight female rats (8-12 weeks, 300-350 ... -
Effects of vincamine on testicular dysfunction in alloxan-induced diabetic male rats
Parlar Köprülü, Rabia Edibe; Okur, Mehmet Evren; Kolbaşı, Bircan; Keskin, İlknur; Özbek, Hanefi (Brieflands, 2022)Background: Diabetes mellitus (DM) is frequently linked with problems of several organ systems, including retinopathy, neuropathy, and nephropathy. Additionally, patients have changes in sexual functioning, such as decreased ... -
Efficacy of one-hour negative pressure wound therapy and magnetic field energy in wound healing
Özer, Aysel Yıldız; Keskin, İlknur; Keleştemur, Taha; Aytürk, Nilüfer; Ersavaş, Cenk; Günal, Mehmet Yalçın (MA Healthcare Ltd, 2024)Objective: Wound healing is an important aspect of health but needs further research to identify the effects and interactions of different treatment approaches on healing. The aims of this study were to investigate the ... -
Erkek infertilitesinde seminal leptin seviyelerinin semen parametreleri ve dna fragmantasyonu ile ilişkisi
Amaç: Bu çalışmamızda insan semen leptin düzeylerini ve semen parametreleri ile ilişkisinin incelenmesi amaçlanmıştır. Materyal ve Metod: YNormal ve oligoastenoteratospermik 30 hastalık gruplar oluşturuldu. Hastaların semen ... -
Erkek yaşı sperm parametrelerini etkiliyor mu? Türk popülasyonuna ait ilk seri
AMAÇ: Çalışmanın amacı, infertilite araştırma amacıyla elde edilmiş 1402 semen örneğinde, baba yaşı ile semen parametreleri (konsantrasyon, motilite, progresif motilite, morfoloji, akrozomal indeks, semen hacmi) arasındaki ... -
Evaluation of apoptosis pathway of geraniol on ishikawa cells
Kuzu, Betül; Cüce, Gökhan; Çınar Ayan, İlknur; Gültekin, Burcu; Canbaz, Halime Tuba; Dursun, Hatice Gül; Şahin, Zafer; Keskin, İlknur; Kalkan, Sabiha Serpil (Routledge, 2021)Endometrial cancer is the most common type of cancer in the female reproductive system. Geraniol is acyclic monoterpene alcohol derived from essential oils of aromatic plants. This study aimed to investigate the apoptosis ... -
Evaluation of hepatoprotective and antidiabetic activity of Alchemilla mollis
Özbek, Hanefi; Bahadır Acıkara, Özlem; Keskin, İlknur; Kırmızı, Neriman İpek; Özbilgin, Serkan; Öz Ergene, Burçin; Kurtul, Ekin; Özrenk, Bade Cevriye; Tekin, Mehmet; Saltan, Gülçin (Elsevier Masson SAS, 2017)Alchemilla mollis (Buser) Rothm aerial part and root methanolic-water extracts were evaluated for their hepatoprotective activity on carbon tetrachloride induced hepatotoxicity and hypoglycemic activity on alloxan-induced ... -
Evaluation of neuroprotection by melatonin against adverse effects of prenatal exposure to a nonsteroidal anti-inflammatory drug during peripheral nerve development
Keskin, İlknur; Kaplan, Süleyman; Kalkan, Serpil; Sütçü, Mustafa; Ülkay, Muzaffer Başak; Esener, Burak (Pergamon Elsevier Science, 2015)The potential ability of melatonin to protect against impairment of the fetal peripheral nerve system due to maternal consumption of diclofenac sodium (DS) was investigated. Eighty-four pregnant rats were divided into seven ... -
Examination of the effect of xenogeneic mesenchymal stem cells and conditioned medium on cartilage graft viability: A rabbit model
Ünlü, Abdullah; Bülbül, Muhammet Volkan; Kolbaşı Erkan, Bircan; Özdemir, İlkay; Keskin, İlknur; Sütçü, Mustafa (Korean Society for Aesthetic Plastic Surgery, 2023)Background Since cartilage, unlike skin, does not contain vessels, it obtains nutrition by diffusion. This reduces graft viability, resulting in problems such as reductions in size, changes in shape, and resorption of the ... -
Experimentally induced metamorphosis in highly regenerative axolotl (ambystoma mexicanum) under constant diet restructures microbiota
Demircan, Turan; Ovezmyradov, Guvanch; Yıldırım, Berna; Keskin, İlknur; İlhan, Ayşe Elif; Fesçioğlu, Ece Cana; Öztürk, Gürkan; Yıldırım, Süleyman (Nature Publishing Group, 2018)Axolotl (Ambystoma mexicanum) is a critically endangered salamander species and a model organism for regenerative and developmental biology. Despite life-long neoteny in nature and in captive-bred colonies, metamorphosis ... -
Exposure to tumescent solution significantly increases phosphorylation of perilipin in adipocytes
BACKGROUND: Lidocaine and epinephrine could potentially decrease adipocyte viability, but these effects have not been substantiated. The phosphorylation status of perilipin in adipocytes may be predictive of cell viability. ... -
Expression of pro-apoptotic and anti-apoptotic proteins in granulosa cells of women with diminished ovarian reserve
Bulgurcuoğlu Kuran, Sibel; Altun, Ayşe; Karamustafaoğlu Balcı, Burçin; Keskin, İlknur; Hocaoğlu, Meryem (Springer, 2022)Purpose To evaluate the expressions of caspase-3 and cytochrome c and heat shock protein 70 (Hsp70) in granulosa cells (GCs) from women with normal ovarian reserve (NOR) and diminished ovarian reserve (DOR) undergoing ... -
Fare östrus siklusu'nun farklı fazlarında plin2 ve plin3 ekspresyonu
Giriş: Puberteye kadar birinci mayozun profaz evresinde bekleyen primordiyal foliküllerden birkaçı puberte ile birlikte, hormonal uyarı altında her ay tekrarlayan bir serüvene başlar. Bu süreçte ovaryumun stromal hücreleri ... -
Fresh versus frozen blastocyst transfer outcomes deriven from the same ICSI cycle in male factor infertility
Karabulut, Seda; Kutlu, Pelin; Korkmaz, Oya; Bülbül, Muhammet Volkan; Keskin, İlknur (IMR Press Limited, 2021)The aim of this study was to investigate the clinical outcomes of fresh and frozen-thawed blastocyst transfer deriven from the same ICSI cycle because of male infertility. 2372 couples undergoing a total of 5075 ICSI cycles ... -
A histological atlas of the tissues and organs of neotenic and metamorphosed axolotl
Demircan, Turan; İlhan, Ayşe Elif; Aytürk, Nilüfer; Yıldırım, Berna; Öztürk, Gürkan; Keskin, İlknur (Elsevier GmbH, 2016)Axolotl (Ambystoma Mexicanum) has been emerging as a promising model in stem cell and regeneration researches due to its exceptional regenerative capacity. Although it represents lifelong lasting neoteny, induction to ... -
A histopathological evaluation of ovarian hyperstimulation syndrome on reproductive and vital organs and the role of the VEGF-PKA pathway in a mouse model
Karabulut, Seda; Korkmaz, Oya; Erdem Altun, Ceren; Keskin, İlknur (Karger, 2021)Ovarian hyperstimulation syndrome (OHSS) is one of the most common and iatrogenic complications of in vitro fertilization therapy, which is an exaggerated response to excess hormones resulting in the development of a large ... -
In 2D and 3D cell culture models, effects of endothelial cells on E-cadherin / β-catenin expression levels and spheroid sizes in ishikawa cells
Kalender, Mervenur; Bülbül, Muhammet Volkan; Kolbaşı, Bircan; Keskin, İlknur (Asian Pacific Organization for Cancer Prevention, 2022)Increasing evidence shows that three dimensional cell culture models better reflect the in vivo tumor microenvironment than two dimensional cell culture models. Co-culture models are ideal cell culture models for understanding ... -
Intracytoplasmic morphologically selected sperm injection, but for whom?
Karabulut, Seda; Aksünger, Özlem; Korkmaz, Oya; Eren Gözel, Hilal; Keskin, İlknur (Cambridge University Press, 2019)Intracytoplasmic sperm injection (ICSI) is performed in cases of infertility by injecting a motile and morphologically normal sperm cell under a routine ×400 magnification at which is hard to distinguish morphologically ... -
Leptin in sperm analysis can be a new indicator
Önel, Tuğçe; Ayla, Şule; Keskin, İlknur; Parlayan, Cüneyd; Yiğitbaşı, Türkan; Kolbaşı, Bircan; Varlı Yelke, Tuba; Şenel Ustabaş, Tuğba (Elsevier GMBH, 2019)Purpose Radiotherapy, chemotherapy, various tumors and invasive surgery can result in ejaculatory dysfunction and testicular insufficiency. Sperm cryopreservation is the only method which can provide a baby for couples. ... -
Male infertility, azoozpermia and cryptozoospermia incidence among three infertility clinics in Turkey
Karabulut, Seda; Keskin, İlknur; Kutlu, Pelin; Delikara, Nuri; Atvar, Özhan; Öztürk, Metin İshak (AVES İbrahim Kara, 2018)Objective: Semen parameters are directly correlated with the infertility of the male. Incidence rates of male factor infertility, azoospermia and cryptozoospermia differ according to many factors such as geographic region, ...