ORCID "0000-0002-0675-1839" Makale Koleksiyonu için listeleme
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Leptin in sperm analysis can be a new indicator
Önel, Tuğçe; Ayla, Şule; Keskin, İlknur; Parlayan, Cüneyd; Yiğitbaşı, Türkan; Kolbaşı, Bircan; Varlı Yelke, Tuba; Şenel Ustabaş, Tuğba (Elsevier GMBH, 2019)Purpose Radiotherapy, chemotherapy, various tumors and invasive surgery can result in ejaculatory dysfunction and testicular insufficiency. Sperm cryopreservation is the only method which can provide a baby for couples. ... -
Limitations of cross-talk between osteosarcoma and bone marrow-derived mesenchymal stem cells
Başbınar, Yasemin; Uysal, Tuğba; Karaca, Caner; Daşkın, Ezgi; Meco, Hanife Ecenur; Pakdemirli, Ahu; Yiğitbaşı, Türkan; Ellidokuz, Hülya (Aves Press Ltd., 2019)Objectives: Metastasis is a multi-step process which leads the tumor cells to escape from primer tumor region due to their need to gain malign phenotypes. While the effect of bone marrow-derived mesenchymal stem cells upon ... -
Methylparaben induces malformations and alterations on apoptosis, oxidant-antioxidant status, ccnd1 and myca expressions in zebrafish embryos
Ateş, Perihan Seda; Ünal, İsmail; Üstündağ, Ünsal Veli; Alturfan, Ahmet Ata; Yiğitbaşı, Türkan; Emekli Alturfan, Ebru (Wiley, 2018)Methylparabens (MP) are widely used as preservatives in cosmetics, pharmacy, and food industry. Although acute toxicity studies in animals indicated that parabens are not significantly toxic, the effects of chronic exposure ... -
A novel biochemical marker for community-acquired pneumonia: Ischemia-modified albumin
Bolatkale, Mustafa; Düger, Mustafa; Ülfer, Gözde; Can, Çağdaş; Acara, Ahmet Çağdaş; Yiğitbaşı, Türkan; Seyhan, Ekrem Cengiz; Bulut, Mehtap (W.B. Saunders, 2017)Introduction Community-acquired pneumonia (CAP) is a frequent cause of hospitalization and a leading cause of mortality worldwide. Early diagnosis and the initiation of appropriate antibiotic therapy are essential to reduce ... -
On the relationship between serum apelin levels and some parameters related to oxidative stress and energy metabolism in obese and non-obese
Daşkın Fakıoğlu, Fatma Betül; Yiğitbaşı, Türkan; Emekli, Nesrin (University of Istanbul, 2017)Adipose tissue plays an important role in energy balance by secretion of various adipokines. Obesity is excessive fat accumulation in the body. The aim of this study is to examine the association of apelin, an adipokine ... -
The optimal method to measure polyamines in serum by using HPLC fluorescence detector
Çakan, Orhan; Hacıhasanoğlu Çakmak, Neziha; Bayramoğlu, Feyza; Yiğitbaşı, Türkan (Istanbul Medipol University, 2023)Measurement of polyamines (putrescine, spermidine and spermine) is important in the monitoring of many metabolic events, as well as in cancer prognosis. However, the lack of method standardization and validation for the ... -
Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
Ateş, Nilay; Çağlayan, Aysun; Balçıkanlı, Zeynep; Sertel, Elif; Beker, Mustafa Çağlar; Dilsiz, Pelin; Çağlayan, Ahmet Burak; Çelik, Süleyman; Daşdelen, Muhammed Furkan; Çağlayan, Berrak; Yiğitbaşı, Türkan; Özbek, Hanefi; Doeppner, Thorsten Roland; Hermann, Dirk Matthias; Kılıç, Ertuğrul (Academic Press Inc., 2022)Lithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its ... -
Preclinical evaluation of scorzonera sp root extracts and major compounds against acute hepatotoxicity induced by carbon tetrachloride
Özbek, Hanefi; Bahadır Acıkara, Özlem; Keskin, İlknur; Kırmızı, Neriman İpek; Yiğitbaşı, Türkan; Sakul, Ayşe Arzu; İşcan, Gülçin Saltan (Wolters Kluwer Medknow Publications, 2017)Evaluation of hepatoprotective activities of Scorzonera roots and their major compounds, was aimed in current study. Scorzonera latifolia, S. tomentosa, S. mollis ssp. szowitsii, S. parviflora and S. cana var. jacquiniana ... -
Preoperative screening for COVID-19: Results from a clinical diagnostic laboratory
Aydoğan, Okan; Gözün Şaylan, Ezgi; Güven, Özlem; Ayaz, Akif; Yiğitbaşı, Türkan (Istanbul University, 2022)Objective: The study aimed to determine what proportion of Turkiye’s preoperative patient population has tested positive for COVID-19 and to ascertain whether the increasing or decreasing trend in the numbers of positive ... -
Prognostic and predictive role of liquid biopsy in lung cancer patients
Göksel, Tuncay; Özgür, Su; Tetik Vardarlı, Aslı; Koç, Altuğ; Soydaner Karakuş, Haydar; Özdemir, Taha Reşid; Erdoğan, Kadri Murat; Aldağ, Ceyda; Veral, Ali; Başbınar, Yasemin (Frontiers Media SA, 2024)Introduction Lung cancer (LC) is a leading cause of cancer-related mortality worldwide. Approximately 80% of LC cases are of the non-small cell lung cancer (NSCLC) type, and approximately two-thirds of these cases are ... -
Relationship between interleukin 33 and tissue factor in non-diabetic and diabetic obese patients
Çakıcı, Çağrı; Yiğitbaşı, Türkan; Alagöz, Maide Hacer; Yiğit, Pakize; Emekli, Nesrin (Istanbul Medipol University, 2021)The aim of the study is to investigate the relationship between tissue factor (TF) and Interleukin-33 (IL-33) and biochemical parameters in diabetic obese and non-diabetic obese patients. 21 healthy controls, 25 non-diabetic ... -
The role of makorin ring finger protein-3, kisspeptin, and neurokinin B in the physiology of minipuberty
Atay, Enver; Kılınç, Suna; Ülfer, Gözde; Yiğitbaşı, Türkan; Çakıcı, Çağrı; Turan, Murat; Ceran, Ömer; Atay, Zeynep (Walter de Gruyter GmbH, 2021)Background: There is no data regarding the interrelationships of circulating Makorin Ring Finger Protein-3 (MKRN3), Kisspeptin (KISS1), and Neurokinin B (NKB) concentrations during minipuberty in humans.Objective: To ... -
The role of thiol/disulfide homeostasis in psoriasis: Can it be a new marker for inflammation?
Doǧa Üstüner, Pelin; Balevi, Ali; Özdemir, Mustafa; Olmuşçelik, Oktay; Ülfer, Gözde; Yiğitbaşı, Türkan (Deri Zührevi Hastalıklar Derneği, 2018)Background and Design: Psoriasis vulgaris is a chronic, systemic, inflammatory disease presenting with oxidative stress and tissue inflammation. Thiol and disulfide levels have been shown to increase in inflammatory diseases ... -
Rotenone impairs oxidant/antioxidant balance both in brain and intestines in zebrafish
Ünal, İsmail; Üstündağ, Ünsal Veli; Ateş, Perihan Seda; Eğilmezer, Gizem; Alturfan, Ahmet Ata; Yiğitbaşı, Türkan; Emekli Alturfan, Ebru (Taylor & Francis Ltd, 2019)Aim of the study: Rotenone is a commonly used pesticide that inhibits complex I of the mitochondrial electron transport system. Rotenone exposed rats demonstrate many characteristics of Parkinson Disease (PD). Oxidative ... -
Seldi-tof-ms profiling of metastatic phenotype in histopathological subtypes of breast cancer
Yiğitbaşı, Türkan; Çalıbaşı Kocal, Gizem; Büyükuslu, Nihal; Atahan, Murat Kemal; Küpeli, Hakan; Yiğit, Seyran; Tarcan, Ercüment; Baskın, Yasemin (Bentham Science Publishers Ltd, 2018)Background: Early detection of breast cancer is a key to the success of breast cancer management. Serum proteome analysis using Surface-Enhanced Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry (SELDI-TOF-MS) ... -
Serum amylase levels can predict hospitalization and operation rates
Baskın, Yasemin; Yiğitbaşı, Türkan; Büyükuslu, Nihal; Çalıbaşı Koçal, Gizem; Üstüner, Füsun; Arslan, Banu; Ellidokuz, Hülya (Aves Press Ltd, 2018)Objective:The levels of serum amylase is an indicator of several diseases. Therefore, a routine amylase test is frequently requested in hospital emergency admissions. This research aims to evaluate the hospitalization and ... -
Serum concentration of ghrelin, oxidative stress and lipid parameters in obese subjects
Zora, Sevilay; Yiğitbaşı, Türkan; Ülfer, Gözde; Emekli, Nesrin (Istanbul University Press, 2018)Objective: Ghrelin is a hormone with peptide structure. It has fatty tissue and increases appetite. Obesity is a multifactorial chronic disease characterized by an increase in fat tissue. Fat tissue, like the endocrine ... -
Targeting the tumor metabolism by oxamate potentiates the impact of chemotherapeutics in colorectal cancer cells
Çalıbaşı Koçal, Gizem; Çakıcı, Çağrı; Toksöz, Feriha; İnanç Sürer, Seniz; Sever, Tolga; Başbınar, Yasemin; Yiğitbaşı, Türkan (Dokuz Eylül University Institute of Health Sciences, 2021)Purpose: Cancer cells promote lactate formation via pyruvate rather than oxidative phosphorylation by programming their metabolism to maintain proliferation under the Warburg effect. It has shown that the altered metabolic ... -
Verteporfin mediated sequence dependent combination therapy against ovarian cancer cell line
Erdem, Sultan Sibel; Akgül Obeidin, Vildan; Yiğitbaşı, Türkan; Tümer, S. Serranur; Yiğit, Pakize (Elsevier Science Sa, 2018)Ovarian Cancer is one of the deadliest gynecological cancer showing high resistance to chemotherapy. Non overlapping and synergistic combination therapies are the best option to overcome this multi-pathological silent ... -
White LED light exposure inhibits the development and xanthophore pigmentation of zebrafish embryo
Üstündağ, Ünsal Veli; Çalışkan-Ak, Esin; Ateş, Perihan Seda; Ünal, İsmail; Eğilmezer, Gizem; Yiğitbaşı, Türkan; Alturfan, Ahmet Ata; Emekli-Alturfan, Ebru (Nature Publishing Group, 2019)Circadian rhythm in all living organisms is disturbed continuously by artificial light sources and artificial lighting has become a hazard for public health. Circadian rhythm of melatonin maintains high levels of melatonin ...