dc.contributor.author | Karan, Belgin | |
dc.contributor.author | Erbay, Gürcan | |
dc.contributor.author | Koç, Zafer | |
dc.contributor.author | Pourbagher, Ayşin | |
dc.contributor.author | Yıldırım, Sedat | |
dc.contributor.author | Ağıldere, Ahmet Muhteşem | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:50:57Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T19:50:57Z | |
dc.date.issued | 2016 | en_US |
dc.identifier.citation | Karan, B., Erbay, G., Koç, Z., Pourbagher, A., Yıldırım, S. ve Ağıldere, A. M. (2016). Utility of diffusion-weighted MRI to detect changes in liver diffusion in benign and malignant distal bile duct obstruction: The influence of choice of b-values. Canadian Association of Radiologists Journal, 67(4), 395-401. https://dx.doi.org/10.1016/j.carj.2016.03.006 | en_US |
dc.identifier.issn | 0846-5371 | |
dc.identifier.issn | 1488-2361 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.carj.2016.03.006 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/2114 | |
dc.description | WOS: 000388250400013 | en_US |
dc.description | PubMed ID: 27592163 | en_US |
dc.description.abstract | Purpose: The study sought to evaluate the potential of diffusion-weighted magnetic resonance imaging to detect changes in liver diffusion in benign and malignant distal bile duct obstruction and to investigate the effect of the choice of b-values on apparent diffusion coefficient (ADC). Methods: Diffusion-weighted imaging was acquired with b-values of 200, 600, 800, and 1000 s/mm(2). ADC values were obtained in 4 segments of the liver. The mean ADC values of 16 patients with malignant distal bile duct obstruction, 14 patients with benign distal bile duct obstruction, and a control group of 16 healthy patients were compared. Results: Mean ADC values for 4 liver segments were lower in the malignant obstruction group than in the benign obstruction and control groups using b = 200 s/mm(2) (P < .05). Mean ADC values of the left lobe medial and lateral segments were lower in the malignant obstruction group than in the benign obstructive and control groups using b = 600 s/mm2 (P < .05). Mean ADC values of the right lobe posterior segment were lower in the malignant and benign obstruction groups than in the control group using b = 1000 s/mm(2) (P < .05). Using b = 800 s/mm(2), ADC values of all 4 liver segments in each group were not significantly different (P > .05). There were no correlations between the ADC values of liver segments and liver function tests. Conclusion: Measurement of ADC shows good potential for detecting changes in liver diffusion in patients with distal bile duct obstruction. Calculated ADC values were affected by the choice of b-values. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Biliary Obstruction | en_US |
dc.subject | Diffusion-Weighted Imaging | en_US |
dc.subject | Liver Fibrosis | en_US |
dc.subject | Magnetic Resonance Imaging | en_US |
dc.subject | B-Value | en_US |
dc.title | Utility of diffusion-weighted MRI to detect changes in liver diffusion in benign and malignant distal bile duct obstruction: The influence of choice of b-values | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Canadian Association of Radiologists Journal | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı | en_US |
dc.identifier.volume | 67 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 395 | en_US |
dc.identifier.endpage | 401 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.carj.2016.03.006 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.identifier.scopusquality | Q2 | en_US |