Utility of diffusion-weighted MRI to detect changes in liver diffusion in benign and malignant distal bile duct obstruction: The influence of choice of b-values
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info:eu-repo/semantics/openAccessTarih
2016Yazar
Karan, BelginErbay, Gürcan
Koç, Zafer
Pourbagher, Ayşin
Yıldırım, Sedat
Ağıldere, Ahmet Muhteşem
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Karan, B., Erbay, G., Koç, Z., Pourbagher, A., Yıldırım, S. ve Ağıldere, A. M. (2016). Utility of diffusion-weighted MRI to detect changes in liver diffusion in benign and malignant distal bile duct obstruction: The influence of choice of b-values. Canadian Association of Radiologists Journal, 67(4), 395-401. https://dx.doi.org/10.1016/j.carj.2016.03.006Özet
Purpose: The study sought to evaluate the potential of diffusion-weighted magnetic resonance imaging to detect changes in liver diffusion in benign and malignant distal bile duct obstruction and to investigate the effect of the choice of b-values on apparent diffusion coefficient (ADC). Methods: Diffusion-weighted imaging was acquired with b-values of 200, 600, 800, and 1000 s/mm(2). ADC values were obtained in 4 segments of the liver. The mean ADC values of 16 patients with malignant distal bile duct obstruction, 14 patients with benign distal bile duct obstruction, and a control group of 16 healthy patients were compared. Results: Mean ADC values for 4 liver segments were lower in the malignant obstruction group than in the benign obstruction and control groups using b = 200 s/mm(2) (P < .05). Mean ADC values of the left lobe medial and lateral segments were lower in the malignant obstruction group than in the benign obstructive and control groups using b = 600 s/mm2 (P < .05). Mean ADC values of the right lobe posterior segment were lower in the malignant and benign obstruction groups than in the control group using b = 1000 s/mm(2) (P < .05). Using b = 800 s/mm(2), ADC values of all 4 liver segments in each group were not significantly different (P > .05). There were no correlations between the ADC values of liver segments and liver function tests. Conclusion: Measurement of ADC shows good potential for detecting changes in liver diffusion in patients with distal bile duct obstruction. Calculated ADC values were affected by the choice of b-values.
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Canadian Association of Radiologists JournalCilt
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