Başlık için Eczacılık Fakültesi listeleme
Toplam kayıt 339, listelenen: 64-83
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CORRECTION to: Clinical and demographic characteristics and two-year efficacy and safety data of 508 multiple sclerosis patients with fingolimod treatment (Archives of Neuropysychiatry, 60, 23)
(Turkish Neuropsychiatric Society, 2023)The name of the author Gökçe Sözer was mistakenly written as Gökçe Sezer. The correct name and institution are as follows. -
Coumarins from the Dichloromethane Root Extract of Heptaptera triquetra and Their Cytotoxic Activities
(ACG Publications, 2023)A known dihydrofuranocoumarin ester; deltoin (1), together with five known sesquiterpene coumarin ethers; umbelliprenin (2), farnesyl scopoletin (3), karatavicinol (4), colladonin (5), colladin (6), and a novel sesquiterpene ... -
Current status of mucoadhesive gel systems for buccal drug delivery
(Bentham Science Publishers Ltd, 2021)Background: Buccal drug delivery is a fascinating research field. Gel-based formulations present potent characteristics as buccal systems since they have great physicochemical properties. Methods: Among the various gels, ... -
Cypsela micro-macromorphological characteristics of selected taxa of Centaurea L. from Turkey and their systematic importance
(Museum National d'Histoire Naturelle, 2023)In this study, the cypsela micro-macromorphological characteristics of 15 Centaurea L. taxa, from the seven sections from Turkey were investigated using Light Microscopy and Scanning Electron Microscopy techniques. The ... -
Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
(MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ... -
Cytotoxic activity of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin
(Istanbul Medipol University, 2022)Cytotoxic activities of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichlorometh-ane extract of the fruits of H. anatolica showed the ... -
Cytotoxic activity of the root and fruit extracts of Heptaptera anisoptera (DC.) Tutin
(İstanbul Medipol University, 2020)Cytotoxic activities of the root and fruit extracts of Heptaptera anisoptera (DC.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the roots of H. anisoptera showed ... -
Cytotoxic effects of various lactic acid bacteria on Caco-2 cells
(Scientific and Technical Research Council of Turkey, 2015)Probiotics are live microbial food supplements that can be considered a functional food. They benefit the health of a host animal by maintaining their intestinal microbial balance. Most probiotic microorganisms are lactic ... -
Cytotoxic effects of Weissella confusa on human colon adenocarcinoma cells (Caco-2 cells)
(Wiley-Blackwell, 2011)… -
Cytotoxic sesquiterpene coumarins from the roots of heptaptera cilicica
(ACG Publications, 2021)Preliminary 2-day cancer cell screening assays indicated that the dichloromethane extract of the roots of Heptaptera cilicica showed relatively strong cytotoxic activity. Eleven sesquiterpene coumarin ethers with potent ... -
Cytotoxic, antiproliferative and apoptotic effects of new benzimidazole derivatives on A549 lung carcinoma and C6 glioma cell lines
(Bentham Science Publishers, 2015)Benzimidazole ring is a versatile structure which has been extensively utilized in medicinal chemistry. Since we are working on 1,2-disubstutited benzimidazoles, we have reported new antitumor active derivatives. As a ... -
Cytotoxicity screening of some Turkish plants against renal cancer cells
(Marmara University, 2023)In this contribution, we performed cytotoxicity screening of 51 extracts from 17 plant species, representing 14 families growing in Turkey. Cytotoxic activities of the dichloromethane, ethyl acetate, and methanol extracts ... -
Design and characterization of nanocarriers loaded with Levofloxacin for enhanced antimicrobial activity; Physicochemical properties, in vitro release and oral acute toxicity
(Faculdade de Ciencias Farmaceuticas (Biblioteca), 2019)Inorganic and carbon based nanomaterials are widely used against several diseases, such as cancer, autoimmune diseases as well as fungi and bacteria colonization. In this work, Santa Barbara Amorphous mesoporous silica ... -
Design and synthesis of new donepezil analogs derived from arylpiperazine scaffold as acetylcholinesterase inhibitors
(Taylor & Francis Ltd, 2020)Newly synthesized 4-substituted phenyl-2-(4-substituted phenylpiperazine-1-yl)thiazole derivatives (4a-v) were evaluated in terms of their acetylcholinesterase (AChE) inhibition activities. Twenty-two compounds were tested ... -
Design and synthesis of novel cylopentapyrazoles bearing 1,2,3-thiadiazole moiety as potent antifungal agents
(Elsevier, 2020)In drug-resistant phytopathogenic fungi, there has been extensive research on microbiological and antifungal drug development. In this study, a novel series of cylopentapyrazole bearing a 1,2,3-thiadiazole ring 2a-e were ... -
Design and synthesis of stable N-[2-(Aryl/heteroaryl substituted)ethyl] propanamide derivatives of (S)-ketoprofen and (S)-ibuprofen as non-ulcerogenic anti-inflammatory and analgesic agents
(University of Istanbul, 2016)The carboxylic acid groups of (S) ketoprofen and (S) ibuprofen were brought into reaction with substituted ethylamine derivatives to form (S)-2-(4-isobutylphenyl)- and (S)-2-(3-benzoylphenyl)-N-[2-(aryl/heteroaryl substituted) ... -
Design, synthesis and biological evaluation of novel tetralone/indanone containing thiosemicarbazone derivatives with selective COX-2 inhibition as anticancer agents
(Elsevier B.V., 2023)A series of novel tetralone/indanone moiety-bearing thiosemicarbazone derivatives were synthesized and evaluated for their biological activities. The structural elucidations of the compounds were performed by IR spectroscopy, ... -
Determination and evaluation of acidity constants of some imidazole and thiazole linked acetamide compounds
(Anadolu University, 2016)In this work, the effect of substituents on the acidity constants of some acetamide derivatives was investigated. The acidity constants of nine acetamide derivatives were determined at 25 °C using a UV spectrophotometric ... -
Determination of aflatoxins and ochratoxin a levels in nuts and dried fruits in Turkey with evaluation of the estimated daily intake
(VUP Food Research Institute, 2023)A total of 140 samples, including nuts and dried fruits sold in the province of Istanbul, Turkey, were examined for the presence of aflatoxins and ochratoxin A (OTA) by high-performance liquid chromatography (HPLC), which ... -
Determination of mycotoxins by HPLC, LC-MS/MS and health risk assessment of the mycotoxins in bee products of Turkey
(NLM (Medline), 2023)The aim of this study is to determine the levels of deoxynivalenol (DON), HT-2 toxin (HT2), T-2 toxin (T2), and ochratoxin A (OTA) in bee products (bee pollen, propolis, honey and royal jelly) available in Turkey. In ...