Başlık için Eczacılık Fakültesi listeleme
Toplam kayıt 339, listelenen: 49-68
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Chitosan modification-enhanced silencing effect of Ad5-shPDGF-D vector in breast cancer cell line MDA-MB-231
(Bentham Science Publishers, 2023)Background: Gene therapeutics are being developed to treat metastatic breast tumors, which are mostly resistant to conventional therapies. Targeting platelet-derived growth factor-D (PDGF-D) is a viable approach because ... -
Chitosan-based buccal mucoadhesive bilayer tablets enhance the bioavailability of tizanidine hydrochloride by bypassing the first-pass metabolism
(2024)Tizanidine hydrochloride (TZN) is an antimuscarinic agent used in the treatment of pain-related spasms, multiple sclerosis, and stroke-related spasticity. It has low oral bioavailability (40 %) due to excessive first-pass ... -
Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine
(Elsevier B.V., 2023)Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to extensive first-pass metabolism and is ... -
Chronobiological efficacy of combined therapy of pelargonium sidoides and melatonin in acute and persistent cases of COVID-19: A hypothetical approach
(Springer, 2023)Since the outbreak of the first SARS-CoV-2 epidemic in China, pharmacists have rapidly engaged and developed strategies for pharmaceutical care and supply. According to the guidelines of the International Pharmaceutical ... -
Clinical and demographic characteristics and two-year efficacy and safety data of 508 multiple sclerosis patients with fingolimod treatment (vol 60, pg 23, 2023)
(Turkish Neuropsychiatric Society, 2023)Copyright of Archives of Neuropsychiatry / Noropsikiatri Arsivi is the property of Turkish Association of Neuropsychiatry and its content may not be copied or emailed to multiple sites or posted to a listserv without the ... -
Combination of exercise and caloric restriction ameliorates nearly complete deleterious effects of aging on cardiovascular hemodynamic and antioxidant system parameters
(Marmara University, 2020)Aging is a progressive and catabolic process by cells of the body are broken down. Study scrutinized the effects of exercise and caloric restriction in cardiovascular hemodynamics and antioxidant system parameters. Rats ... -
Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-beta reveals anticancer effect in breast cancer
(Wiley, 2023)Background: Platelet derived growth factors (PDGF)-D and the expression of its receptor increase in neoplastic progression of cancer. Co-silencing of growth factor and receptor can be suggested as an important strategy for ... -
A comparative investigation on the in vitro anti-inflammatory, antioxidant and antimicrobial potentials of subextracts from the aerial parts of Daphne oleoides Schreb. subsp oleoides
(Elsevier, 2017)Daphne oleoides Schreb. subsp. oleoides is an evergreen shrub which is known for its folkloric usage against various ailments such as arthritic and infectious diseases. The aim of the present study was to comparatively ... -
Comparative study of the anti-inflammatory, antioxidant and urease inhibitory activities of Eryngium kotschyi Boiss. and E. campestre L. var. virens (Link) Weins extracts
(Marmara University Press, 2020)Despite widespread traditional usage of Eryngium species in Anatolia (Turkey), only a limited number of scientific studies exists on E. kotschyi, an endemic species. Previously, extracts from E. campestre and E. kotschyi ... -
Comparison of 3 doses of aloe vera and burn drugs in market on burnt rat models
(İstanbul Medipol University, 2018)Burn injuries are an incident that can have serious traumatic consequences. Degree of tissue damage depends on height of heat and duration of contact. It can be classified as 4 different burn degrees. Herbal treatments can ... -
Comparison of chemical profiles of aronia melanocarpa fruit extracts
(Turkish Science and Technology Publishing (TURSTEP), 2023)The chokeberry plant, which is native to North America and the south of Canada, is a deciduous, shrub-shaped, berry-like plant belonging to the Rosaceae family, which survives for many years. It is seen as a plant that ... -
Comparison of In vitro Anti-inflammatory, COX-1/COX-2 and LOX inhibitory activities of Malva sylvestris L. leaves and flowers extract
(Georg Thieme Verlag KG, 2023)... -
Comparison of inhaled and intraperitoneal formaldehyde toxicity in rats and the evaluation of the effects of melatonin
(Elsevier Ireland Ltd, 2016)Formaldehyde (FA) is a genotoxic substance that causes deleterious effects on the nervous system, respiratory system, and reproductive system as a result of occupational exposure. FA is also classified as human carcinogen ... -
Comparison of intestinal permeability of nebivolol hydrochloride loaded solid lipid nanoparticles with commercial nebivolol tablet
(Marmara University, 2018)The oral application of drugs is the most popular route for achieving systemic effects, nevertheless, it is limited by difficulties related to physicochemical properties of the drug. Solid lipid nanoparticles (SLNs) are ... -
A contraindication to metfromin therapy: Renal impairment - Adherence to prescribing guidelines at a hospital in Turkey
(University of Istanbul, 2018)Objective: The aim of this study was to investigate whether renal functions of the patients were monitored and checked before and during metformin treatment as recommended in guidelines or whether they were disregarded and ... -
CORRECTION to: Clinical and demographic characteristics and two-year efficacy and safety data of 508 multiple sclerosis patients with fingolimod treatment (Archives of Neuropysychiatry, 60, 23)
(Turkish Neuropsychiatric Society, 2023)The name of the author Gökçe Sözer was mistakenly written as Gökçe Sezer. The correct name and institution are as follows. -
Coumarins from the Dichloromethane Root Extract of Heptaptera triquetra and Their Cytotoxic Activities
(ACG Publications, 2023)A known dihydrofuranocoumarin ester; deltoin (1), together with five known sesquiterpene coumarin ethers; umbelliprenin (2), farnesyl scopoletin (3), karatavicinol (4), colladonin (5), colladin (6), and a novel sesquiterpene ... -
Current status of mucoadhesive gel systems for buccal drug delivery
(Bentham Science Publishers Ltd, 2021)Background: Buccal drug delivery is a fascinating research field. Gel-based formulations present potent characteristics as buccal systems since they have great physicochemical properties. Methods: Among the various gels, ... -
Cypsela micro-macromorphological characteristics of selected taxa of Centaurea L. from Turkey and their systematic importance
(Museum National d'Histoire Naturelle, 2023)In this study, the cypsela micro-macromorphological characteristics of 15 Centaurea L. taxa, from the seven sections from Turkey were investigated using Light Microscopy and Scanning Electron Microscopy techniques. The ... -
Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
(MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ...