Ara
Toplam kayıt 333, listelenen: 41-50
Quality of life assessment with EORTC QLQ in patients with multiple myeloma: Multicenter study
(Galenos Publishing House, 2022)
Objective: Both the length of the treatment period and the diversity of the agents used in the treatment significantly affect the quality of life (QoL) of the patients with multiple myeloma (MM). With the aid of the EORTC ...
Identification of PDE10A related proteins via proteomic analysis
(İnönü University Faculty of Medicine, 2022)
Aim: Phosphodiesterase 10A (PDE10A) regulates the expression of secondary messengers of cyclic adenosine monophosphate and cyclic guanosine monophosphate, which control several intracellular signaling pathways. Recently, ...
Evaluation of nutritional status with Healthy Eating Index (HEI-2010) of syrian refugees living outside the refugee camps
(MDPI, 2023)
Nutrition is a public health issue. Amongst populations of refugees, unmet nutritional needs have been identified. The aim of this study was to evaluate the nutritional status of Syrian refugees living outside the refugee ...
Experimentally induced metamorphosis in highly regenerative axolotl (ambystoma mexicanum) under constant diet restructures microbiota
(Nature Publishing Group, 2018)
Axolotl (Ambystoma mexicanum) is a critically endangered salamander species and a model organism for regenerative and developmental biology. Despite life-long neoteny in nature and in captive-bred colonies, metamorphosis ...
Digenic DUOX1 and DUOX2 mutations in cases with congenital hypothyroidism
(Oxford University Press Inc, 2017)
Context: The DUOX2 enzyme generates hydrogen peroxide (H2O2), a crucial electron acceptor for the thyroid peroxidase-catalyzed iodination and coupling reactions mediating thyroid hormone biosynthesis. DUOX2 mutations result ...
Als2 silencing affects the expression of two NF-κB targeted genes via uxt in adult mouse primary spinal motor neuron culture
(Logos Medical Publishing, 2018)
Aim: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder affecting motor neurons. Als2 is one of the genes that cause ALS, and its mutations leads to loss of function in alsin protein. The interaction between ...
Longitudinal 16S rRNA data derived from limb regenerative tissue samples of axolotl ambystoma mexicanum
(Nature Publishing Group, 2019)
The Mexican axolotl (Ambystoma mexicanum) is a critically endangered species and a fruitful amphibian model for regenerative biology. Despite growing body of research on the cellular and molecular biology of axolotl limb ...
A pooled RT-PCR testing strategy for more efficient Covid-19 pandemic management
(Elsevier, 2022)
Objectives: RT-PCR testing is indispensable in Covid-19 pandemic management. With the spread of the pandemic with emerging variants, the RT-PCR capacity is overburdened and new strategies and capabilities need to be ...
Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice
(Nature Research, 2022)
Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals will affect circadian rhythm and the relation of such a decrease ...
Neurons from human mesenchymal stem cells display both spontaneous and stimuli responsive activity
(Public Library of Science, 2020)
Mesenchymal stem cells have the ability to transdifferentiate into neurons and therefore one of the potential adult stem cell source for neuronal tissue regeneration applications and understanding neurodevelopmental ...