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The impact of metabolic syndrome on increased risk of thyroid nodules and size
(Sage Publications Inc, 2018)
Aim: The present research aimed to determine the relation between metabolic syndrome (MetS) and thyroid volume and nodule prevalence among Turkish population patients. Methods: This retrospective cohort study was carried ...
Allyl isothiocyanate enhances brain neuronal plasticity proteins via inhibition of inflammation proteins
(Lippincott Williams & Wilkins, 2018)
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Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism
(American Society for Clinical Investigation Inc, 2018)
Defects in genes mediating thyroid hormone biosynthesis result in dyshormonogenic congenital hypothyroidism (CH). Here, we report homozygous truncating mutations in SLC26A7 in 6 unrelated families with goitrous CH and show ...
Confocal laser endomicroscopy and optical coherence tomography for the diagnosis of prostate cancer: A needle-based, in vivo feasibility study protocol (Ideal phase 2a)
(JMIR Publications, Inc, 2018)
Background: Focal therapy for prostate cancer has been proposed as an alternative treatment to whole-gland therapies in selected men to diminish side effects in localized prostate cancer. As nowadays imaging cannot offer ...
DNA methylation pattern of TM6SF2 influences NAFLD progression in genotype-dependent manner
(Elsevier Science Bv, 2019)
Background and aims: Non-alcoholic fatty liver disease (NAFLD) arises due to complex interaction of genetic and environmental factors. Evidence suggests that transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is ...
Functional and anatomical dissection of feeding circuits
(Wiley, 2016)
This chapter reviews the application of new genetically encoded tools in feeding circuits that regulate appetite. Rapid activation and inhibition of agouti related peptide (AgRP) neurons conclusively established a causal ...
DeepMQ: A deep learning approach based myelin quantification in microscopic fluorescence images
(IEEE Computer Society, 2018)
Oligodendrocytes wrap around the axons and form the myelin. Myelin facilitates rapid neural signal transmission. Any damage to myelin disrupts neuronal communication leading to neurological diseases such as multiple sclerosis ...
Guiding empiric treatment for serious bacterial infections via point of care beta-lactamase characterization
(Ieee-Inst Electrical Electronics Engineers Inc, 2016)
Fever is one of the most common symptoms of illness in infants and represents a clinical challenge due to the potential for serious bacterial infection. As delayed treatment for these infections has been correlated with ...