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Toplam kayıt 119, listelenen: 1-10
DNA methylation pattern of TM6SF2 influences NAFLD progression in genotype-dependent manner
(Elsevier Science Bv, 2019)
Background and aims: Non-alcoholic fatty liver disease (NAFLD) arises due to complex interaction of genetic and environmental factors. Evidence suggests that transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is ...
Patient-specific induced pluripotent stem cells for cardiac disease modeling
(Walter de Gruyter GMBH, 2019)
Reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) via induction of pluripotency genes is one of the most influential scientific breakthroughs during the last decade. Behind this breakthrough ...
Investigating side effects of existing drugs used in Covid-19 treatment
(Institute of Electrical and Electronics Engineers Inc., 2020)
Following the rapid spread and evolution of the novel Corona virus starting in December 2019, the lack of a vaccine or a medication that proved to be effective for Covid-19 was addressed as a major concern by the World ...
The investigation of genetic etiology in familial cases with congenital hypothyroidism
(Karger, 2019)
Background: Congenital hypothyroidism(CH) is the most common neonatal endocrinological disorder in the world. Although most of the CH is sporadic, some genetic defects are responsible from the etiology. The aim of this ...
Floresan mikroskop görüntülerinde miyelin segmentasyonu
(Institute of Electrical and Electronics Engineers Inc., 2019)
Aksonların etrafına sarılmış¸ miyelin kılıf, hızlı bir şekilde sinyal iletimini sağlar ve deformasyonu, Multipl Skleroz (MS) gibi çeşitli nörodejeneratif hastalıklara neden olur. Aday ilaç geliştirilmesi için, miyelinizasyonun ...
Which ultrasound or MRI characteristics demonstrate the highest diagnostic accuracy in identifying malignancy in males with indeterminate lesions of the testis? A systematic review
(Elsevier, 2021)
Introduction & Objectives: The use of Scrotal Ultrasound (SUS) has resulted in increased detection of indeterminate testicular lesions, resulting in a clinical and management challenge. The gold standard of treatment has ...
Evaluation of chirality for withdrawn drugs
(Wiley, 2021)
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Effect of social isolation on the brain injury following focal cerebral ischemia in mice and proteomic approach for identifying possible cellular pathways
(Wiley, 2021)
Social isolation has become a significant part of our everyday life during the Covid-19 pandemic, resulting in drastic effects on physiological wellbeing. It was shown that loneliness or psychosocial stress such as social ...
Development of mucoadhesive modified kappa-carrageenan/pectin patches for controlled delivery of drug in the buccal cavity
(Wiley, 2022)
In this study, modified kappa-carrageenan/pectin hydrogel patches were fabricated for treatment of buccal fungal infections. For this purpose, kappa-carrageenan-g-acrylic acid was modified with different thiolated agents ...
Utilization trend of gastric acid-suppressing agents in relation to analgesics
(Wiley, 2022)
Background: Controversies exist about excessive use of gastric acid-suppressing agents or lack of adequate indications, especially when co-prescribed with analgesics for gastroprotection. We aimed to analyze the nationwide ...