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Metaproteogenomic analysis of saliva samples from Parkinson's disease patients with cognitive impairment
(Nature Portfolio, 2023)
Cognitive impairment (CI) is very common in patients with Parkinson's Disease (PD) and progressively develops on a spectrum from mild cognitive impairment (PD-MCI) to full dementia (PDD). Identification of PD patients at ...
Technical aspects and clinical limitations of sperm DNA fragmentation testing in male infertility: A global survey, current guidelines, and expert recommendations
(Korean Society for Sexual Medicine and Andrology, 2023)
Purpose: Sperm DNA fragmentation (SDF) is a functional sperm abnormality that can impact reproductive potential, for which four assays have been described in the recently published sixth edition of the WHO laboratory manual ...
Active shrinkage protects neurons following axonal transection
(Elsevier Inc., 2023)
Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ...
When bladder and brain collide: Is there a gender difference in the relationship between urinary incontinence, chronic depression, and anxiety?
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
In longitudinal and cross-sectional studies, depression and anxiety have been associated with urinary incontinence (UI) in women. However, this association has not been studied in men. Utilizing data from the 2008 Turkish ...
The impact of chiral switch on drug labeling in Turkey: Indication, posology, and adverse effects
(Marmara University, 2023)
Objective: Chiral switch, which involves replacing racemic drugs to market them as pure enantiomers, is presumed to improve efficacy and safety. Data on how chiral switch-related changes are represented in summary of product ...
A longitudinal study of the association between depression, anxiety and stress symptoms of university students in Serbia with excessive social media use before and during COVID-19 pandemic
(Frontiers Media SA, 2023)
Background: Besides the well known good side of social media, it cannot be denied some of its negative effects. This two-phase study aimed to find out whether the usage of social media during the COVID-19 pandemic showed ...
Age-associated resilience against ischemic injury in mice exposed to transient middle cerebral artery occlusion
(Springer, 2023)
Ischemic stroke is the leading cause of death and disability. Although stroke mainly affects aged individuals, animal research is mostly one on young rodents. Here, we examined the development of ischemic injury in young ...
Examining the tapestry of mental health crises in low-& middle-income countries: An intercontinental analysis of the contributing factors and instructive approaches
(University of Faisalabad, 2023)
In recent decades, the intricate landscape of mental health challenges has become a focal point of global concern, with particular urgency in Low-and Middle-Income Countries (LMICs). This manuscript delves into the ...
Triggers and regulation: The gut microbiome in rheumatoid arthritis
(Taylor and Francis Ltd., 2023)
Introduction Rheumatoid arthritis is a chronic inflammatory disease marked by systemic symptoms and joint degeneration. Interestingly, the development and progression of rheumatoid arthritis have been linked to the microbiome, ...
The impact of single-use digital flexible cystoscope for double J removal on hospital costs and work organization: A multicentric evaluation
(SAGE Publications Ltd, 2023)
Background: Isiris-alpha (R) is a single-use digital flexible cystoscope with an integrated grasper designed for double J (DJ) stent removal. Aim of this study was to conduct a multicentric evaluation of the costs and ...