Başlık için Uluslararası Tıp Fakültesi listeleme
Toplam kayıt 475, listelenen: 355-374
-
Pancreatic tumor detection by convolutional neural networks
(Institute of Electrical and Electronics Engineers Inc., 2022)Artificial Intelligence and its sub-branches like Machine Learning (ML) and Deep Learning (DL) applications have the potential to have positive effects that can directly affect human life. Medical imaging provides a way ... -
Patient-reported outcome measures using modified urethral stricture surgery: Patient-reported outcome measure for direct visual internal urethrotomy and nontransecting urethroplasty for short nontraumatic bulbar urethral stricture - A prospective comparative observational study from a university teaching hospital
(Wolters Kluwer Medknow Publications, 2023)Purpose: To evaluate the patient-reported outcomes of primary direct visual internal urethrotomy (DVIU) and nontransecting bulbar urethroplasty techniques (NTBU) for the short segment (<2 cm) nontraumatic bulbar urethral ... -
Patient-specific induced pluripotent stem cells for cardiac disease modeling
(Walter de Gruyter GMBH, 2019)Reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) via induction of pluripotency genes is one of the most influential scientific breakthroughs during the last decade. Behind this breakthrough ... -
The phosphatidylinositol-3 kinase/Akt pathway mediates melatonin's neuroprotective activity after focal cerebral ischemia
(Springer Heidelberg, 2014)… -
Phosphodiesterase 10A deactivation induces long-term neurological recovery, peri-infarct remodeling and pyramidal tract plasticity after transient focal cerebral ischemia in mice
(Academic Press Inc., 2022)The phosphodiesterase (PDE) superfamily comprises enzymes responsible for the cAMP and cGMP degradation to AMP and GMP. PDEs are abundant in the brain, where they are involved in several neuronal functions. High PDE10A ... -
Phosphodiesterase 10A is a critical target for neuroprotection in a mouse model of ischemic stroke
(Springer, 2022)Phosphodiesterase 10A (PDE10A) hydrolyzes adenosine 3 ',5 '-cyclic monophosphate (cAMP) and guanosine 3 ',5 '-cyclic monophosphate (cGMP). It is highly expressed in the striatum. Recent evidence implied that PDE10A may be ... -
Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
(Academic Press Inc., 2022)Lithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its ... -
Physiological and pharmacological roles of melatonin in the pathophysiological components of cellular injury after ischemic stroke
(NLM (Medline), 2020)Apart from its metabolic or physiological functions, melatonin has a potent cytoprotective activity in the physiological and pathological conditions. It is synthetized by the pineal gland and released into the blood ... -
Poloxamer-188 and d-α-tocopheryl polyethylene glycol succinate (TPGS-1000) mixed micelles integrated orodispersible sublingual films to improve oral bioavailability of ebastine in vitro and in vivo characterization
(MDPI, 2021)Orodispersible sublingual films (OSFs) composed of hydrophilic polymers were loaded with poloxamer-188 and d-alpha-tocopheryl polyethylene glycol succinate (TPGS-1000) mixed micelles to improve the oral bioavailability of ... -
Polycystic ovary syndrome: A disorder of reproductive age, its pathogenesis, and a discussion on the emerging role of herbal remedies
(Frontiers Media SA, 2022)Polycystic ovary syndrome (PCOS) is a very common, complex, and heterogeneous endocrine disorder of women that involves a combination of environmental and genetic factors. PCOS affects women of growing age particularly at ... -
A pooled RT-PCR testing strategy for more efficient Covid-19 pandemic management
(Elsevier, 2022)Objectives: RT-PCR testing is indispensable in Covid-19 pandemic management. With the spread of the pandemic with emerging variants, the RT-PCR capacity is overburdened and new strategies and capabilities need to be ... -
Positioning Europe for the epitranscriptomics challenge
(Taylor and Francis Inc., 2018)The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built. ... -
Post-COVID-19 pain syndrome: A descriptive study in Turkish population
(Korean Pain Society, 2022)Background: The new type of corona virus has a wide range of symptoms. Some people who have COVID-19 can experience long-term effects from their infection, known as post-COVID conditions. The authors aimed to investigate ... -
Post-trauma acinetobacter baumannii meningitis treatment approach
(Turkısh Assoc Trauma Emergency Surgery, 2024)Acinetobacter baumannii, associated with nosocomial infections, is considered a significant mortality risk if not adequately addressed. A. baumannii infections typically occur after surgery or trauma. Our patient developed ... -
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
(Frontiers Media S.A., 2022)Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ... -
Pre-use ureteroscope contamination after high level disinfection: Reprocessing effectiveness and the relation with cumulative ureteroscope use
(Lippincott Williams and Wilkins, 2019)Purpose: We assessed the frequency of preoperative and persistent microbial contamination of flexible ureteroscopes after reprocessing and the relation of contamination to cumulative ureteroscope use. Materials and Methods: ... -
Preclinical molecular signatures of spinal cord functional restoration: Optimizing the metamorphic axolotl (ambystoma mexicanum) model in regenerative medicine
(Mary Ann Liebert, 2020)Regenerative medicine offers hope for patients with diseases of the central and peripheral nervous system. Urodele amphibians such as axolotl display an exceptional regenerative capacity and are considered as essential ... -
Preoperative risk factors of airway complications in adult lung transplant recipients: A systematic review and meta-analysis
(Baycinar Medical Publishing, 2023)Background: In this systematic review and meta-analysis, we aimed to identify recipient-related preoperative risk factors for airway complications following lung transplantation in adults. Methods: Articles published between ... -
Preoperative screening for COVID-19: Results from a clinical diagnostic laboratory
(Istanbul University, 2022)Objective: The study aimed to determine what proportion of Turkiye’s preoperative patient population has tested positive for COVID-19 and to ascertain whether the increasing or decreasing trend in the numbers of positive ...
