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Toplam kayıt 117, listelenen: 101-110
Beyond the therapeutic effect of RTMS in Alzheimer’s disease: A possible neuroprotective role of hippocampal BDNF?: A minireview
(Bentham Science Publishers B.V., 2018)
Repetitive transcranial magnetic stimulation (rTMS) is a well known non-invasive brain stimulation procedure which is capable of inducing the expression of the hippocampal BDNF that has been already shown to exert significant ...
Evaluation of light-emitting diode photobiomodulation on bone healing of rat calvarial defects
(Taylor & Francis, 2015)
One of the major problems in modern dentistry is the recovery of bone defects. The aim of this prospective experimental study was to evaluate the effect of light-emitting diode (LED) photobiomodulation therapy on bone ...
The therapeutic role of minocycline in Parkinson's disease
(Bioexcel Publishing LTD, 2019)
Minocycline, a semisynthetic tetracycline-derived antibiotic, has been shown to exert anti-apoptotic, anti-inflammatory, and antioxidant effects. Furthermore, there is rapidly growing evidence suggesting that minocycline ...
Focused ultrasound and NXY-059 in experimental cerebral ischemia: A new therapeutic opportunity?
(Bentham Science Publishers, 2016)
troke is the third leading cause of morbidity and mortality worldwide. Many deleterious cellular pathways have been proposed to explain the molecular pathogenesis of this clinically devastating disease [1, 2]. The ...
ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury
(Nature Research, 2022)
Platelet activation plays a critical role in thrombosis. Inhibition of platelet activation is a cornerstone in treatment of acute organ ischemia. Platelet ACKR3 surface expression is independently associated with all-cause ...
Postacute effects of kisspeptin-10 on neuronal injury induced by L-methionine in rats
(Wiley-Blackwell, 2014)
Apart from its effect on the regulation of reproductive function, recent studies indicate that kisspeptin may play roles in the antioxidant defense system. The antioxidant defense system and oxidative stress contribute to ...
Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?
(Wiley, 2017)
Sleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms ...
Therapeutic role of rifampicin in Alzheimer's disease
(Wiley, 2018)
Rifampicin exerts significant brain protective functions in multiple experimental models. Here we summarize the underlying mechanisms of the neuroprotective and pro-cognitive effects of rifampicin that are mediated by its ...
Evidence that osteogenic and neurogenic differentiation capability of epidural adipose tissue-derived stem cells was more pronounced than in subcutaneous cells
(Tübitak Scientific & Technical Research Council Turkey, 2020)
Background/aim: The management of dura-related complications, such as the repairment of dural tears and reconstruction of large dural defects, remain the most challenging subjects of neurosurgery. Numerous surgical techniques ...
Phosphodiesterase 10A deactivation induces long-term neurological recovery, peri-infarct remodeling and pyramidal tract plasticity after transient focal cerebral ischemia in mice
(Academic Press Inc., 2022)
The phosphodiesterase (PDE) superfamily comprises enzymes responsible for the cAMP and cGMP degradation to AMP and GMP. PDEs are abundant in the brain, where they are involved in several neuronal functions. High PDE10A ...