Browsing Tıp Fakültesi by Subject "Pseudomonas Exotoxin"
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IL13 fused pseudomonas exotoxin targets various cancers in vitro
(International Institute of Anticancer Research, 2021)Background/Aim: Pseudomonas exotoxin (PE) is one of the most widely used toxins in the construction of therapeutic fusion proteins in pre-clinical studies followed by phase trials. In principle, PE acts by blocking protein ... -
IL13R alpha 2-and EGFR-targeted pseudomonas exotoxin potentiates the TRAIL-mediated death of GBM cells
(Spandidos Publications Ltd, 2021)Glioblastomas (GBMs) are refractory to current treatments and novel therapeutic approaches need to be explored. Pro-apoptotic tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is tumor-specific and has been ...