Plasma leptin, nesfatin 1, NPY, and zinc levels in obese and metabolic syndrome children
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info:eu-repo/semantics/openAccessAttribution-NonCommercial 4.0 Internationalhttps://creativecommons.org/licenses/by-nc/4.0/Date
2023Author
Aydoğdu, AdnanÜnal, Ömer
Baltacı, Saltuk Buğra
Menevşe, Esma
Moğulkoç, Rasim
Erdem, Said Sami
Büyükinan, Muammer
Baltacı, Abdulkerim Kasım
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Aydoğdu, A., Ünal, Ö., Baltacı, S. B., Menevşe, E., Moğulkoç, R. ve Erdem, S. S. (2023). Plasma leptin, nesfatin 1, NPY, and zinc levels in obese and metabolic syndrome children. European Journal of Therapeutics, 29(4), 856-865. https://dx.doi.org/10.58600/eurjther1760Abstract
Objective: The aim of this study is to investigate the relationship between leptin, nesfatin 1 and NPY hormones and zinc in boys and girls diagnosed with metabolic syndrome and obesity.
Methods: This study included a total of 6 groups. Group 1 Boy Control, Group 2 Girl Control, Group 3 Obese Boys, Group 4 Obese Girls, Group 5 Boys with Metabolic Syndrome, Group 2 with Girls with Metabolic Syndrome. Plasma leptin, nesfatin-1, NPY (by ELISA method) and serum zinc (by AA method) levels were determined in blood samples obtained from the subjects.
Results: Leptin and zinc levels were significantly higher both in boy and girl patients with metabolic syndrome than in obese and control children. Nesfatin-1 and NPY levels were significantly lower both in girl and boy obese and metabolic syndrome children compared to their control groups.
Conclusion: In the current study a significant increase in plasma leptin and serum zinc levels and a significant decrease of plasma nesfatin-1 and NPY levels were observed in boys and girls with metabolic syndrome. The findings of our study show that leptin, nesfatin-1 and NPY levels may be important biomarkers in the assessment of metabolic syndrome risk in both girls and boys.
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European Journal of TherapeuticsVolume
29Issue
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