dc.contributor.author | Aydoğdu, Adnan | |
dc.contributor.author | Ünal, Ömer | |
dc.contributor.author | Baltacı, Saltuk Buğra | |
dc.contributor.author | Menevşe, Esma | |
dc.contributor.author | Moğulkoç, Rasim | |
dc.contributor.author | Erdem, Said Sami | |
dc.contributor.author | Büyükinan, Muammer | |
dc.contributor.author | Baltacı, Abdulkerim Kasım | |
dc.date.accessioned | 2024-03-12T05:31:15Z | |
dc.date.available | 2024-03-12T05:31:15Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Aydoğdu, A., Ünal, Ö., Baltacı, S. B., Menevşe, E., Moğulkoç, R. ve Erdem, S. S. (2023). Plasma leptin, nesfatin 1, NPY, and zinc levels in obese and metabolic syndrome children. European Journal of Therapeutics, 29(4), 856-865. https://dx.doi.org/10.58600/eurjther1760 | en_US |
dc.identifier.issn | 2564-7784 | |
dc.identifier.issn | 2564-7040 | |
dc.identifier.uri | https://dx.doi.org/10.58600/eurjther1760 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/12355 | |
dc.description.abstract | Objective: The aim of this study is to investigate the relationship between leptin, nesfatin 1 and NPY hormones and zinc in boys and girls diagnosed with metabolic syndrome and obesity.
Methods: This study included a total of 6 groups. Group 1 Boy Control, Group 2 Girl Control, Group 3 Obese Boys, Group 4 Obese Girls, Group 5 Boys with Metabolic Syndrome, Group 2 with Girls with Metabolic Syndrome. Plasma leptin, nesfatin-1, NPY (by ELISA method) and serum zinc (by AA method) levels were determined in blood samples obtained from the subjects.
Results: Leptin and zinc levels were significantly higher both in boy and girl patients with metabolic syndrome than in obese and control children. Nesfatin-1 and NPY levels were significantly lower both in girl and boy obese and metabolic syndrome children compared to their control groups.
Conclusion: In the current study a significant increase in plasma leptin and serum zinc levels and a significant decrease of plasma nesfatin-1 and NPY levels were observed in boys and girls with metabolic syndrome. The findings of our study show that leptin, nesfatin-1 and NPY levels may be important biomarkers in the assessment of metabolic syndrome risk in both girls and boys. | en_US |
dc.description.sponsorship | Selcuk University | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Pera Yayincilik Hizmetleri | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Attribution-NonCommercial 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Children | en_US |
dc.subject | Metabolic Syndrome | en_US |
dc.subject | Obesity | en_US |
dc.subject | Leptin | en_US |
dc.subject | Nesfatin 1 | en_US |
dc.subject | NPY | en_US |
dc.subject | Zinc | en_US |
dc.title | Plasma leptin, nesfatin 1, NPY, and zinc levels in obese and metabolic syndrome children | en_US |
dc.type | article | en_US |
dc.relation.ispartof | European Journal of Therapeutics | en_US |
dc.department | İstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-9752-7508 | en_US |
dc.identifier.volume | 29 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 856 | en_US |
dc.identifier.endpage | 865 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.58600/eurjther1760 | en_US |
dc.institutionauthor | Baltacı, Saltuk Buğra | |
dc.identifier.wos | 001162350300020 | en_US |