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dc.contributor.authorAydoğdu, Adnan
dc.contributor.authorÜnal, Ömer
dc.contributor.authorBaltacı, Saltuk Buğra
dc.contributor.authorMenevşe, Esma
dc.contributor.authorMoğulkoç, Rasim
dc.contributor.authorErdem, Said Sami
dc.contributor.authorBüyükinan, Muammer
dc.contributor.authorBaltacı, Abdulkerim Kasım
dc.date.accessioned2024-03-12T05:31:15Z
dc.date.available2024-03-12T05:31:15Z
dc.date.issued2023en_US
dc.identifier.citationAydoğdu, A., Ünal, Ö., Baltacı, S. B., Menevşe, E., Moğulkoç, R. ve Erdem, S. S. (2023). Plasma leptin, nesfatin 1, NPY, and zinc levels in obese and metabolic syndrome children. European Journal of Therapeutics, 29(4), 856-865. https://dx.doi.org/10.58600/eurjther1760en_US
dc.identifier.issn2564-7784
dc.identifier.issn2564-7040
dc.identifier.urihttps://dx.doi.org/10.58600/eurjther1760
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12355
dc.description.abstractObjective: The aim of this study is to investigate the relationship between leptin, nesfatin 1 and NPY hormones and zinc in boys and girls diagnosed with metabolic syndrome and obesity. Methods: This study included a total of 6 groups. Group 1 Boy Control, Group 2 Girl Control, Group 3 Obese Boys, Group 4 Obese Girls, Group 5 Boys with Metabolic Syndrome, Group 2 with Girls with Metabolic Syndrome. Plasma leptin, nesfatin-1, NPY (by ELISA method) and serum zinc (by AA method) levels were determined in blood samples obtained from the subjects. Results: Leptin and zinc levels were significantly higher both in boy and girl patients with metabolic syndrome than in obese and control children. Nesfatin-1 and NPY levels were significantly lower both in girl and boy obese and metabolic syndrome children compared to their control groups. Conclusion: In the current study a significant increase in plasma leptin and serum zinc levels and a significant decrease of plasma nesfatin-1 and NPY levels were observed in boys and girls with metabolic syndrome. The findings of our study show that leptin, nesfatin-1 and NPY levels may be important biomarkers in the assessment of metabolic syndrome risk in both girls and boys.en_US
dc.description.sponsorshipSelcuk Universityen_US
dc.language.isoengen_US
dc.publisherPera Yayincilik Hizmetlerien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectChildrenen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectObesityen_US
dc.subjectLeptinen_US
dc.subjectNesfatin 1en_US
dc.subjectNPYen_US
dc.subjectZincen_US
dc.titlePlasma leptin, nesfatin 1, NPY, and zinc levels in obese and metabolic syndrome childrenen_US
dc.typearticleen_US
dc.relation.ispartofEuropean Journal of Therapeuticsen_US
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)en_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalıen_US
dc.authorid0000-0002-9752-7508en_US
dc.identifier.volume29en_US
dc.identifier.issue4en_US
dc.identifier.startpage856en_US
dc.identifier.endpage865en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.58600/eurjther1760en_US
dc.institutionauthorBaltacı, Saltuk Buğra
dc.identifier.wos001162350300020en_US


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