dc.contributor.author | Al, Serdar | |
dc.contributor.author | Ulusoy, Oktay | |
dc.contributor.author | Asilsoy, Suna | |
dc.contributor.author | Uzuner, Nevin | |
dc.contributor.author | Kangallı, Özge | |
dc.contributor.author | Atay, Özge | |
dc.contributor.author | Odaman Al, Işık | |
dc.contributor.author | Ateş, Oğuz | |
dc.date.accessioned | 2023-10-06T11:24:34Z | |
dc.date.available | 2023-10-06T11:24:34Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Al, S., Ulusoy, O., Asilsoy, S., Uzuner, N., Kangallı, Ö., Atay, Ö. ... Ateş, O. (2023). A successful treatment approach in 2 patients with type 1 plasminogen deficiency: Intratracheal application of fresh frozen plasma and tissue plasminogen activator. Journal of Pediatric Hematology/Oncology, 45(7), 423-426. https://doi.org/10.1097/MPH.0000000000002698 | en_US |
dc.identifier.issn | 1536-3678 | |
dc.identifier.issn | 1077-4114 | |
dc.identifier.uri | https://doi.org/10.1097/MPH.0000000000002698 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/11536 | |
dc.description.abstract | BACKGROUND: Respiratory system involvement is common in congenital plasminogen deficiency. Although many treatment approaches have been tried, there is still no definitive treatment for respiratory system involvement. OBSERVATIONS: We report 2 congenital plasminogen deficiency cases, who presented with severe respiratory symptoms, for whom a novel treatment modality was tried. After intravenous administration of FFP (fresh frozen plasma), tissue plasminogen activator and FFP were administered intratracheally, and respiratory system findings improved. CONCLUSIONS: Intratracheal administration of tissue plasminogen activator and FFP is an available treatment modality for patients with lung involvement. Fibrin plaques should be carefully removed and new lesion formation should be prevented. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | NLM (Medline) | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Plasminogen Deficiency | en_US |
dc.subject | Plasminogen | en_US |
dc.subject | Fresh Frozen Plasma | en_US |
dc.subject | Pseudomembranes | en_US |
dc.subject | Respiratory System | en_US |
dc.subject | Congenital | en_US |
dc.title | A successful treatment approach in 2 patients with type 1 plasminogen deficiency: Intratracheal application of fresh frozen plasma and tissue plasminogen activator | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Journal of Pediatric Hematology/Oncology | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | en_US |
dc.authorid | 0000-0003-4292-1409 | en_US |
dc.identifier.volume | 45 | en_US |
dc.identifier.issue | 7 | en_US |
dc.identifier.startpage | 423 | en_US |
dc.identifier.endpage | 426 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1097/MPH.0000000000002698 | en_US |
dc.institutionauthor | Odaman Al, Işık | |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.wos | 001156976000006 | en_US |
dc.identifier.scopus | 2-s2.0-85172711537 | en_US |
dc.identifier.pmid | 37490638 | en_US |
dc.identifier.scopusquality | Q3 | en_US |