Relationship between arterial stiffness parameters and the extent and severity of coronary artery disease

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dc.authorid0000-0003-1919-3183
dc.authorid0000-0002-4607-5724
dc.authorid0000-0001-9975-5507
dc.authorid0000-0001-5825-8627
dc.authorid0000-0002-4951-6716
dc.contributor.authorKızılırmak Yılmaz, Filiz
dc.contributor.authorBabur Güler, Gamze
dc.contributor.authorKaya, Özgür
dc.contributor.authorGüler, Ekrem
dc.contributor.authorDemir, Gültekin Günhan
dc.contributor.authorGüneş, Hacı Murat
dc.contributor.authorOlgun, Fatih Erkam
dc.contributor.authorBarutçu, İrfan
dc.contributor.authorBoztosun, Bilal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:51:35Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:51:35Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000410030800006
dc.description.abstractBackground: The association between arterial stiffness (AS) and coronary artery disease (CAD) has been previously demonstrated. In the present study, we aim to investigate the relationship between various AS parameters and the extent and severity of CAD. Methods: The study population consisted of 411 patients with CAD documented by coronary angiography. We measured various AS parameters including augmentation index (AIx), augmentation pressure (AP), pulse wave velocity (PWV), central systolic pressure (cSys), central diastolic pressure (cDia) and central pulse pressure (cPP) with pulse wave analysis. Angiographic images were used to calculate Gensini score and Syntax score. AS parameters were compared using Gensini score and Syntax score. Results: Syntax score is correlated with age, cSys, cPP, PWV, AP, brachial pulse pressure (bPP), hemoglobin, urea, diabetes mellitus, left main coronary artery disease (p < 0.10 for each). However, Gensini score is correlated only with age, diabetes mellitus, left main coronary artery disease and bPP (p < 0.10 for each). Multivariate analysis revealed age, diabetes mellitus, left main coronary artery disease and bPP as significant predictors of Syntax score; however, for Gensini score, age, diabetes mellitus, gender, left main coronary artery disease, and bPP are determined as predictors. Conclusion: AS parameters are not associated with Syntax score or Gensini score. Apart from traditional risk factors, bPP appears to be the only significant predictor for Syntax score and Gensini score.
dc.identifier.citationKızılırmak Yılmaz, F., Babur Güler, G., Kaya, Ö., Güler, E., Demir, G. G., Güneş, Hacı M. ... Boztosun, B. (2017). Relationship between arterial stiffness parameters and the extent and severity of coronary artery disease. Cor Et Vasa, 59(2), E134-E141. https://dx.doi.org/10.1016/j.crvasa.2016.05.004
dc.identifier.doi10.1016/j.crvasa.2016.05.004
dc.identifier.endpageE141
dc.identifier.issn0010-8650
dc.identifier.issn1803-7712
dc.identifier.issue2
dc.identifier.scopusqualityQ4
dc.identifier.startpageE134
dc.identifier.urihttps://dx.doi.org/10.1016/j.crvasa.2016.05.004
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2244
dc.identifier.volume59
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Bv.
dc.relation.ispartofCor Et Vasaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectArterial Stiffness
dc.subjectGensini Score
dc.subjectSyntax Score
dc.subjectCentral Aortic Pressure
dc.titleRelationship between arterial stiffness parameters and the extent and severity of coronary artery disease
dc.typeArticle

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