PsART-ID inception cohort: Clinical characteristics, treatment choices and outcomes of patients with psoriatic arthritis

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dc.authorid0000-0002-9927-3644
dc.contributor.authorAyan, Gizem
dc.contributor.authorAydın, Sibel Zehra
dc.contributor.authorKimyon, Gezmiş
dc.contributor.authorÖzişler, Cem
dc.contributor.authorTinazzi, İlaria
dc.contributor.authorDoğru, Atalay
dc.contributor.authorOmma, Ahmet
dc.contributor.authorKılıç, Levent
dc.contributor.authorYılmaz, Sema
dc.contributor.authorKüçükşahin, Orhan
dc.contributor.authorGönüllü, Emel
dc.contributor.authorYıldız, Fatih
dc.contributor.authorCan, Meryem
dc.contributor.authorBalkarlı, Ayşe
dc.contributor.authorSolmaz, Dilek
dc.contributor.authorDalkılıç, Ediz
dc.contributor.authorBayındır, Özün
dc.contributor.authorYıldırım Çetin, Gözde
dc.contributor.authorErgülü Esmen, Serpil
dc.contributor.authorErsözlü, Emine Duygu
dc.contributor.authorDuruöz, Mehmet Tuncay
dc.contributor.authorAkyol, Lütfi
dc.contributor.authorKüçük, Adem
dc.contributor.authorBeş, Cemal
dc.contributor.authorÇınar, Muhammet
dc.contributor.authorErden, Abdülsamet
dc.contributor.authorMercan, Rıdvan
dc.contributor.authorBakırcı, Sibel
dc.contributor.authorKaşifoğlu, Timuçin
dc.contributor.authorYazısız, Veli
dc.contributor.authorKalyoncu, Umut
dc.date.accessioned2021-04-06T07:45:19Z
dc.date.available2021-04-06T07:45:19Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractObjectives: Our aim is to understand clinical characteristics, real-life treatment strategies, outcomes of early PsA patients and determine the differences between the inception and established PsA cohorts.Methods: PsArt-ID (Psoriatic Arthritis- International Database) is a multicentre registry. From that registry, patients with a diagnosis of PsA up to 6 months were classified as the inception cohort (n==388). Two periods were identified for the established cohort: Patients with PsA diagnosis within 5-10 years (n = 328), ?10 years (n = 326). Demographic, clinical characteristics, treatment strategies, outcomes were determined for the inception cohort and compared with the established cohorts.Results: The mean (s.d.) age of the inception cohort was 44.7 (13.3) and 167/388 (43.0%) of the patients were male. Polyarticular and mono-oligoarticular presentations were comparable in the inception and established cohorts. Axial involvement rate was higher in the cohort of patients with PsA ?10 years compared with the inception cohort (34.8% vs 27.7%). As well as dactylitis and nail involvement (P = 0.004, P = 0.001 respectively). Both enthesitis, deformity rates were lower in the inception cohort. Overall, 13% of patients in the inception group had a deformity. MTX was the most commonly prescribed treatment for all cohorts with 10.7% of the early PsA patients were given anti-TNF agents after 16 months.Conclusion: The real-life experience in PsA patients showed no significant differences in the disease pattern rates except for the axial involvement. The dactylitis, nail involvement rates had increased significantly after 10 years from the diagnosis and the enthesitis, deformity had an increasing trend over time.
dc.identifier.citationAyan, G., Aydın, S. Z., Kimyon, G., Özişler, C., Tinazzi, İ., Doğru, A. ... Kalyoncu, U. (2021). PsART-ID inception cohort: Clinical characteristics, treatment choices and outcomes of patients with psoriatic arthritis. Rheumatology, 60(4), 1755-1762. https://dx.doi.org/10.1093/rheumatology/keaa663
dc.identifier.doi10.1093/rheumatology/keaa663
dc.identifier.endpage1762
dc.identifier.issn1462-0324
dc.identifier.issn1462-0332
dc.identifier.issue4
dc.identifier.scopusqualityQ1
dc.identifier.startpage1755
dc.identifier.urihttps://dx.doi.org/10.1093/rheumatology/keaa663
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6699
dc.identifier.volume60
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherOxford University Press
dc.relation.ispartofRheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPsoriatic Arthritis
dc.subjectInception Cohort
dc.subjectEarly Disease
dc.titlePsART-ID inception cohort: Clinical characteristics, treatment choices and outcomes of patients with psoriatic arthritis
dc.typeArticle

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