Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
| dc.authorid | 0000-0002-6393-1465 | |
| dc.authorid | 0000-0003-0352-1947 | |
| dc.authorid | 0000-0002-7199-583X | |
| dc.contributor.author | Kazcı, Yusuf Enes | |
| dc.contributor.author | Şahoğlu Göktaş, Sevilay | |
| dc.contributor.author | Aydın, Mehmet Şerif | |
| dc.contributor.author | Karadoğan, Behnaz | |
| dc.contributor.author | Nebol, Aylin | |
| dc.contributor.author | Turhan, Mehmet Uğurcan | |
| dc.contributor.author | Öztürk, Gürkan | |
| dc.contributor.author | Çağavi, Esra | |
| dc.date.accessioned | 2022-08-08T06:30:18Z | |
| dc.date.available | 2022-08-08T06:30:18Z | |
| dc.date.issued | 2022 | |
| dc.department | İstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü | |
| dc.department | İstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Sinirbilim Ana Bilim Dalı | |
| dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı | |
| dc.department | İstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Tıbbi Biyoloji ve Genetik Ana Bilim Dalı | |
| dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı | |
| dc.description.abstract | Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional remodeling contributing to cardiac dysfunction. Although the efferent component of the cardiac nerves has been well described, sensory innervation of the heart has not been defined in detail. Considering its importance, comprehensive description of vagal afferent innervation on the whole heart would enable a better description of autonomic imbalances manifesting as sympathoexcitation and vagal withdrawal in post-ischemic states. To address this issue, we globally mapped the vagal nodose afferent fibers innervating the whole murine heart with unprecedented resolution. By using the Phox2b-Cre | |
| dc.identifier.citation | Kazcı, Y. E., Şahoğlu Göktaş, S., Aydın, M. Ş., Karadoğan, B., Nebol, A., Turhan, M. U. ... Çağavi, E. (2022). Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach. Autonomic Neuroscience: Basic and Clinical, 242. https://doi.org/10.1016/j.autneu.2022.103019 | |
| dc.identifier.doi | 10.1016/j.autneu.2022.103019 | |
| dc.identifier.issn | 1566-0702 | |
| dc.identifier.pmid | 35905544 | |
| dc.identifier.scopus | 2-s2.0-85134827591 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.uri | https://doi.org/10.1016/j.autneu.2022.103019 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/9635 | |
| dc.identifier.volume | 242 | |
| dc.identifier.wos | 000883012500003 | en_US |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.institutionauthor | Kazcı, Yusuf Enes | |
| dc.institutionauthor | Şahoğlu Göktaş, Sevilay | |
| dc.institutionauthor | Aydın, Mehmet Şerif | |
| dc.institutionauthor | Karadoğan, Behnaz | |
| dc.institutionauthor | Nebol, Aylin | |
| dc.institutionauthor | Öztürk, Gürkan | |
| dc.institutionauthor | Çağavi, Esra | |
| dc.language.iso | en | |
| dc.publisher | Elsevier B.V. | |
| dc.relation.ispartof | Autonomic Neuroscience: Basic and Clinical | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.relation.tubitak | info:eu-repo/grantAgreement/TUBITAK/SOBAG/219S332 | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Heart | |
| dc.subject | Myocardial Infarct | |
| dc.subject | Neural Remodeling | |
| dc.subject | Nodose Ganglia | |
| dc.subject | Vagal Afferents | |
| dc.subject | Whole Organ Imaging | |
| dc.title | Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach | |
| dc.type | Article |











