Quercetin enhances human sperm motility in a dose and time dependent manner

dc.authorid0000-0003-3302-5004
dc.authorid0000-0003-2923-5869
dc.authorid0000-0001-7446-472X
dc.authorid0000-0002-7059-1884
dc.contributor.authorKarabulut, Seda
dc.contributor.authorKorkmaz, Oya
dc.contributor.authorErdem Altun, Ceren
dc.contributor.authorDemiroğlu Zergero?lu, Asuman
dc.contributor.authorKeskin, İlknur
dc.date.accessioned2021-01-08T10:22:07Z
dc.date.available2021-01-08T10:22:07Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractThe aim of this study was to investigate the effect of quercetin on the motility of ejaculated human spermatozoa in asthenozoospermic cases by using different doses and exposure times. Semen samples of 94 men were incubated with quercetin at different doses and durations. Sperm motility was analysed in each group, and the results were compared. Compared to control, Quercetin improved sperm motility in each molarity and each interval except 1M. Statistically significant increase was assessed at 0.05 M after 1 hours of incubation, and 0.1 M after two hours of incubation (p<0.05). According to our results, it can be suggested that quercetin has a positive effect on sperm motility on a dose and time dependent manner. This study provides evidence for the potential use of quercetin for sperm preparation to be used in assisted reproduction techniques especially in cases of asthenozoospermia.
dc.identifier.citationKarabulut, S., Korkmaz, O., Erdem Altun, C., Demiroğlu Zergero?lu, A. ve Keskin, İ. (2020). Quercetin enhances human sperm motility in a dose and time dependent manner. Acta Pharmaceutica Sciencia, 58(2), 170-178. https://dx.doi.org/10.23893/1307-2080.APS.05810
dc.identifier.doi10.23893/1307-2080.APS.05810
dc.identifier.endpage178
dc.identifier.issn1307-2080
dc.identifier.issue2
dc.identifier.scopusqualityQ3
dc.identifier.startpage170
dc.identifier.urihttps://dx.doi.org/10.23893/1307-2080.APS.05810
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6212
dc.identifier.volume58
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherIstanbul Medipol University
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSperm
dc.subjectMotility
dc.subjectQuercetin
dc.subjectAsthenozoospermia
dc.titleQuercetin enhances human sperm motility in a dose and time dependent manner
dc.typeArticle

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