Impact of pulsatile perfusion on clinical outcomes of neonates and infants with complex pathologies undergoing cardiopulmonary bypass procedures

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dc.authorid0000-0002-0799-4875
dc.authorid0000-0002-0799-4875
dc.authorid0000-0003-4856-0974
dc.contributor.authorAlkan Bozkaya, Tijen
dc.contributor.authorAkçevin, Atıf
dc.contributor.authorTürkoğlu, Halil
dc.contributor.authorÜndar, Akif
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:37:20Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:37:20Z
dc.date.issued2013
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractThe aim of this clinical trial was to evaluate the pulsatile perfusion mode in pediatric patients who had complex cardiac pathologies according to Jenkins stratifications (category 4) undergoing cardiopulmonary bypass procedures (CPB). Patients with transposition of great arteries (TGA) and ventricular septal defect (VSD) were included in this clinical study. Eighty-nine consecutive pediatric patients undergoing open heart surgery for repair of TGA-VSD were prospectively entered into the study and were randomly assigned to either the pulsatile perfusion group (Group P, n=58) or the nonpulsatile perfusion group (Group NP, n=31). There were no differences between groups in terms of demographical and intraoperative parameters. The pulsatile group needed significantly less inotropic support (P<0.05) and had lower lactate levels (P<0.001), higher urine output (P<0.01), and higher albumin levels (P<0.05). In addition, the pulsatile group had less ICU (P<0.01) and hospital stays (P<0.001). We conclude that the use of pulsatile flow is a better option and should be considered for repair of the complex congenital heart defects.
dc.identifier.citationAlkan Bozkaya, T., Akçevin, A., Türkoğlu, H. ve Ündar, A. (2013). Impact of pulsatile perfusion on clinical outcomes of neonates and infants with complex pathologies undergoing cardiopulmonary bypass procedures. Artificial Organs, 37(1), 82-86. https://dx.doi.org/10.1111/j.1525-1594.2012.01552.x
dc.identifier.doi10.1111/j.1525-1594.2012.01552.x
dc.identifier.endpage86
dc.identifier.issn0160-564X
dc.identifier.issue1
dc.identifier.scopusqualityQ2
dc.identifier.startpage82
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1384
dc.identifier.urihttps://dx.doi.org/10.1111/j.1525-1594.2012.01552.x
dc.identifier.volume37
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofArtificial Organsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectClinical Outcomes
dc.subjectComplex Congenital Heart Surgery
dc.subjectNonpulsatile Flow
dc.subjectPediatric Cardiopulmonary Bypass
dc.subjectPulsatile Flow
dc.subjectVital Organ Recovery
dc.titleImpact of pulsatile perfusion on clinical outcomes of neonates and infants with complex pathologies undergoing cardiopulmonary bypass procedures
dc.typeArticle

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