Association between BNP levels and new-onset atrial fibrillation: A propensity score approach

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dc.contributor.authorKaraba?, Yavuz
dc.contributor.authorRencüzoğulları, İbrahim
dc.contributor.authorÇa?daş, Metin
dc.contributor.authorKarakoyun, Süleyman
dc.contributor.authorYesin, Mahmut
dc.contributor.authorUluganyan, Mahmud
dc.contributor.authorGürsoy, Mustafa Ozan
dc.contributor.authorArtaç, İnanç
dc.contributor.authorİliş, Do?an
dc.contributor.authorGökdeniz, Tayyar
dc.contributor.authorEfe, Süleyman Çağan
dc.contributor.authorTaşar, Onur
dc.contributor.authorTanbo?a, Halil İbrahim
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:50:15Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:50:15Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000444701600011
dc.descriptionPubMed ID: 28707026
dc.description.abstractNew-onset atrial fibrillation (NOAF), a common complication of acute ST-segment elevation myocardial infarction (STEMI), is associated with a poor prognosis. Several clinical and laboratory parameters are reported to be associated with NOAF in patients with STEMI. The aim of the present study was to evaluate the predictive value of plasma BaEurotype natriuretic peptide (BNP) levels for NOAF development and long-term prognosis in STEMI patients undergoing primary percutaneous coronary intervention (pPCI). We retrospectively enrolled 1,928 patients with STEMI who underwent pPCI. After applying exclusion criteria, 1,057 patients were retained in the final study population. Patients with NOAF were compared with patients without NOAF in the entire study population and in a matched group. Patients with NOAF had a significantly higher average plasma BNP level (161 pg/ml, range: 72.3-432) than patients without NOAF in the study population (70.7 pg/ml, range: 70-129; p <0.001) and in the matched group (104.6 pg/ml, range: 47.2-234.5; p = 0.014). Furthermore, the plasma BNP level was found to be an independent predictor of NOAF development (odds ratio [OR]: 1.003; 95% confidence interval [CI]: 1.000-1.005; p = 0.034) and mortality in the long-term follow-up (OR: 1.004; 95% CI: 1.002-1.006; p <0.001). The present study found that a high plasma BNP level was significantly associated with NOAF development in STEMI patients, and was an independent predictor of NOAF development and all-cause mortality during long-term follow-up, regardless of other NOAF risk factors.
dc.identifier.citationKaraba?, Y., Rencüzoğulları, İ., Ça?daş, M., Karakoyun, S., Yesin, M., Uluganyan, M. ... Tanbo?a, H. (2018). Association between BNP levels and new-onset atrial fibrillation: A propensity score approach. Herz, 43(6), 548-554. https://dx.doi.org/10.1007/s00059-017-4598-6
dc.identifier.doi10.1007/s00059-017-4598-6
dc.identifier.endpage554
dc.identifier.issn0340-9937
dc.identifier.issn1615-6692
dc.identifier.issue6
dc.identifier.scopusqualityQ3
dc.identifier.startpage548
dc.identifier.urihttps://dx.doi.org/10.1007/s00059-017-4598-6
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1929
dc.identifier.volume43
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherUrban & Vogel
dc.relation.ispartofHerzen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectB Type Natriuretic Peptide
dc.subjectAtrial Fibrillation
dc.subjectST Segment Elevationmyocardial Infarction
dc.subjectPrognostic Factors
dc.subjectPercutaneous Coronary Intervention
dc.titleAssociation between BNP levels and new-onset atrial fibrillation: A propensity score approach
dc.typeArticle

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