The relationship between hepatic high FIB-4 score and COVID-19 pneumonia

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dc.authorid0000-0002-3793-5251
dc.authorid0000-0002-9815-1848
dc.contributor.authorDemir, Esra
dc.contributor.authorErol, Vedat Buğra
dc.contributor.authorOlmuşçelik, Oktay
dc.contributor.authorKoryürek, Özgül M.
dc.contributor.authorTabak, Ömür
dc.contributor.authorDemir, Bülent
dc.date.accessioned2023-01-17T12:53:24Z
dc.date.available2023-01-17T12:53:24Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground: We aimed to compare the level of hepatic FIB-4 scores between COVID-19 patients who had pneu-monia and COVID-19 patients who had no pneumonia in an attempt to develop a risk assessment after the treat-ment and recovery of active COVID-19 infection. Methods: The study included 80 patients who were consecutively selected and admitted to an internal medicine outpatient clinic for a control examination after COVID-19 infection. Chest tomography was performed on all pa-tients during the COVID-19 infection. Patients were divided into two groups as those with and without lung in-volvement on CT. COVID-19 infection was diagnosed using real-time reverse transcription-polymerase chain re-action (RT-PCR). The hepatic fibrosis 4 (FIB-4) index score was calculated for each patient. The statistical ana-lyses were performed using Student's t-test and chi-squared tests. Results: We found that the increased hepatic FIB-4 index score in patients with pneumonia group was statistically significant compared to the control group (p < 0.001). The regression analysis showed that the hepatic FIB-4 index has significant prognostic efficiencies in both uni-and multivariate models (p < 0.05). Conclusions: The hepatic FIB-4 index appears to be a simple parameter with a good prognostic value in patients with COVID-19 infection.
dc.identifier.citationDemir, E., Erol, V. B., Olmuşçelik, O., Koryürek, Ö. M., Tabak, Ö. ve Demir, B. (2022). The relationship between hepatic high FIB-4 score and COVID-19 pneumonia. Clinical Laboratory, 68(3), 539-544. https://dx.doi.org/10.7754/Clin.Lab.2021.210616
dc.identifier.doi10.7754/Clin.Lab.2021.210616
dc.identifier.endpage544
dc.identifier.issn1433-6510
dc.identifier.issue3
dc.identifier.pmid35254026
dc.identifier.scopus2-s2.0-85125839794
dc.identifier.scopusqualityQ3
dc.identifier.startpage539
dc.identifier.urihttps://dx.doi.org/10.7754/Clin.Lab.2021.210616
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10322
dc.identifier.volume68
dc.identifier.wos000753807200001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDemir, Esra
dc.institutionauthorErol, Vedat Buğra
dc.institutionauthorOlmuşçelik, Oktay
dc.language.isoen
dc.publisherClinical Laboratory Publication
dc.relation.ispartofClinical Laboratoryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCoronavirus Infections
dc.subjectLiver Fibrosis
dc.subjectPneumonia
dc.subjectPrognostic Factors
dc.titleThe relationship between hepatic high FIB-4 score and COVID-19 pneumonia
dc.typeArticle

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