Olfactory and gustatory dysfunctions in COVID-19 patients: From a different perspective

dc.authorid0000-0001-7566-1063
dc.authorid0000-0002-7041-0094
dc.authorid0000-0001-8945-2385
dc.contributor.authorPolat, Burcu
dc.contributor.authorHelvacı Yılmaz, Nesrin
dc.contributor.authorAltın, Gökhan
dc.contributor.authorAtakcan, Zeynep
dc.contributor.authorMert, Ali
dc.date.accessioned2021-09-16T06:56:07Z
dc.date.available2021-09-16T06:56:07Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
dc.description.abstractPurpose: The prevalence of sensory disorders (smell and/or taste) in affected patients has shown a high variability of 5% to 98% during the COVID-19 outbreak, depending on the methodology, country, and study. Loss of smell and taste occurring in COVID-19 cases are now recognized by the international scientific community as being among the main symptoms of the disease. This study investigates loss of smell and taste in outpatients and hospitalized patients with laboratory-confirmed COVID-19 infection. Methods: Enrolled in the study were patients with a positive PCR test for COVID-19. Excluded were patients with chronic rhinosinusitis, nasal polyposis, common cold, influenza, and olfactory/gustatory dysfunction predating the pandemic. Patients were asked about changes in their sense of smell and taste by structured questionnaire. Their status was classified according to severity of the symptoms. Results: A total of 217 patients were included in the study, of whom 129 received outpatient treatment, whereas 88 were hospitalized; mean age was 41.74 years (range18-76), 59.4% were male. At evaluation for olfactory dysfunction, 53.9% of the patients were found to be normal, whereas 33.2% were anosmic. No gustatory dysfunction was found in 49.8% of patients, whereas in those with loss of taste, the most commonly recorded symptom was ageusia. Anosmia was significantly more common in outpatients (P = 0.038). Presentation of chemosensorial symptoms in women was higher than in men (P = 0.009). No correlation was found between olfactory and gustatory dysfunction and age (P = 0.178). Conclusions: About one-half of our patients presented olfactory and/or gustatory deficits, and loss of smell was more common in mild cases. It should be considered; a sudden, severe, and isolated loss of smell and/or taste may also be present in COVID-19 patients who are otherwise asymptomatic. We suggest that identification of persons with these signs and early isolation could prevent spread of the disease in the community.
dc.identifier.citationPolat, B., Helvacı Yılmaz, N., Altın, G., Atakcan, Z. ve Mert, A. (2021). Olfactory and gustatory dysfunctions in COVID-19 patients: From a different perspective. Journal of Craniofacial Surgery, 32(6), 2119-2122. https://dx.doi.org/10.1097/SCS.0000000000007412
dc.identifier.doi10.1097/SCS.0000000000007412
dc.identifier.endpage2122
dc.identifier.issn1049-2275
dc.identifier.issn1536-3732
dc.identifier.issue6
dc.identifier.scopusqualityQ2
dc.identifier.startpage2119
dc.identifier.urihttps://dx.doi.org/10.1097/SCS.0000000000007412
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8185
dc.identifier.volume32
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofJournal of Craniofacial Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAgeusia
dc.subjectAnosmia
dc.subjectCOVID-19
dc.subjectGustatory
dc.subjectHospitalization
dc.subjectOlfactory
dc.subjectSARS-CoV-2
dc.titleOlfactory and gustatory dysfunctions in COVID-19 patients: From a different perspective
dc.typeArticle

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