Recurrent endometrioma in infertile patients has worse outcome than primary endometrioma in response to controlled ovarian hyperstimulation and intrauterine insemination

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dc.authorid0000-0001-9442-2690
dc.contributor.authorKıyak, Hüseyin
dc.contributor.authorKaracan, Tolga
dc.contributor.authorBulut, Berk
dc.contributor.authorÖzyürek, Eser
dc.contributor.authorGedikbaşı, Ali
dc.contributor.authorApi, Murat
dc.date.accessioned2020-01-02T12:01:51Z
dc.date.available2020-01-02T12:01:51Z
dc.date.issued2019
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractObjective: To investigate the difference in the effectiveness of controlled ovarian hyperstimulation and intrauterine insemination (COH + IUI) on pregnancy rates in patients with primary and recurrent endometriomas. Study Design: Multicenter, retrospective cohort study done in 3 tertiary referral centers. Included in the study were (1) primary infertility patients with endometriomas who had no other probable cause for infertility, (2) those who underwent 2 cycles of COH + IUI, provid- ed the sperm test was nor- mal, (3) those who had at least 1 patent fallopian tube, and (4) those whose ovarian reserve was normal with ovulatory cycles. Therapy for COH was hMG (menotropin) or recombinant follicle-stimulating hormone (follitropin alfa, beta) at 75 IU/d starting from day 3. Trigger was done by 5,000-10,000 human chorionic gonadotropin or choriogonadotropin alfa 250 mu g/0.5 mL when the dominant follicle size reached 18 mm. Results: The ongoing pregnancy rates in patients with primary endometrioma were 14.4% per patient and 8.06% per cycle. In patients with recurrent endometrioma, the ongoing pregnancy rates were 6.06% per patient and 3.4% per cycle. Ongoing pregnancy rates were significantly higher in patients with primary endometrioma than in recurrent endometrioma patients. CONCLUSION: COH + IUI may be recommended even before surgery for couples with primary endometriomas when there is no other infertility factor. COH + IUI treatment is not recommended for recurrent endometrioma patients.
dc.identifier.citationHüseyin, K., Tolga, K., Berk, B., Eser, O., Ali, G. ve Murat, A (2019). Recurrent endometrioma in infertile patients has worse outcome than primary endometrioma in response to controlled ovarian hyperstimulation and intrauterine insemination. Journal of Reproductive Medicine, 64(7-8), 282-290.
dc.identifier.endpage290
dc.identifier.issn0024-7758
dc.identifier.issn1943-3565
dc.identifier.issue45511
dc.identifier.scopusqualityQ3
dc.identifier.startpage282
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4865
dc.identifier.volume64
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherScience Printers and Publishers Inc.
dc.relation.ispartofJournal of Reproductive Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAdenomyosis
dc.subjectArtificial Insemination
dc.subjectAssisted Reproductive Techniques
dc.subjectDeep Infiltrative Endometriosis
dc.subjectEndometrioma
dc.subjectEndometriosis
dc.subjectInfertility
dc.subjectIntrauterine Insemination
dc.subjectOvulation Induction
dc.subjectPelvic Pain/Diagnosis
dc.titleRecurrent endometrioma in infertile patients has worse outcome than primary endometrioma in response to controlled ovarian hyperstimulation and intrauterine insemination
dc.typeArticle

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