Serum SCUBE-1 levels and return of spontaneous circulation following cardiopulmonary resuscitation in adult patients

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dc.authorid0000-0002-7675-0014
dc.contributor.authorYılmaz, Cahit
dc.contributor.authorGülen, Bedia
dc.contributor.authorSönmez, Ertan
dc.contributor.authorAkbay, Dursun
dc.contributor.authorSöğüt, Özgür
dc.contributor.authorÖzdemir, Serdar
dc.contributor.authorÖzer, Ömer Faruk
dc.date.accessioned2023-02-08T12:14:07Z
dc.date.available2023-02-08T12:14:07Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Acil Tıp Ana Bilim Dalı
dc.description.abstractBackground SCUBE 1-has been used as a biomarker for the diagnoses of myocardial infarction, stroke, mesenteric ischemia, and gastric cancer in some recent studies. In this study, we investigated the relationship between serum SCUBE-1 levels and return of spontaneous circulation (ROSC) in patients who received cardiopulmonary resuscitation (CPR). Methods Patients over 18 years of age who were not pregnant and received CPR were divided into two groups: those who achieved ROSC and those who died. There were 25 patients in each group. SCUBE-1 and other routine biochemical parameters were studied in blood samples taken at the time of admission. Results There was no significant difference between the age and gender distribution of the patients between the two groups. The SCUBE-1 value of the ROSC group was significantly higher than that of the non-survivor group ( p ? 0.05). At a cut-off value of 9 ng/mL, SCUBE-1 had a sensitivity of 100%, a positive predictive value of 65.8%, specificity of 48%, and a negative predictive value of 100% in predicting ROSC. Conclusions The SCUBE-1 values were found to be significantly higher in the ROSC group compared with the non-survivor group.
dc.identifier.citationYılmaz, C., Gülen, B., Sönmez, E., Akbay, D., Söğüt, Ö., Özdemir, S. ... Özer, Ö. F. (2022). Serum SCUBE-1 levels and return of spontaneous circulation following cardiopulmonary resuscitation in adult patients. Avicenna Journal of Medicine, 12(3), 148-153. https://dx.doi.org/10.1055/s-0042-1755389
dc.identifier.doi10.1055/s-0042-1755389
dc.identifier.endpage153
dc.identifier.issn2231-0770
dc.identifier.issn2249-4464
dc.identifier.issue3
dc.identifier.pmid36092384
dc.identifier.startpage148
dc.identifier.urihttps://dx.doi.org/10.1055/s-0042-1755389
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10413
dc.identifier.volume12
dc.indekslendigikaynakPubMed
dc.institutionauthorGülen, Bedia
dc.language.isoen
dc.publisherMedknow Publications & Media Pvt.
dc.relation.ispartofAvicenna Journal of Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectSCUBE?1 Protein
dc.subjectCardiopulmonary Resuscitation
dc.subjectPeptides
dc.titleSerum SCUBE-1 levels and return of spontaneous circulation following cardiopulmonary resuscitation in adult patients
dc.typeArticle

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