Demographic characteristics, aetiology, and assessment of treatment options in leukocytoclastic vasculitis

dc.authorid0000-0002-4119-9939
dc.contributor.authorÇakıter, Alkım Ünal
dc.contributor.authorKüçük, Özlem Su
dc.contributor.authorBıyık Özkaya, Dilek
dc.contributor.authorTopukçu, Buğçe
dc.contributor.authorOnsun, Nahide
dc.date.accessioned2020-07-14T07:37:08Z
dc.date.available2020-07-14T07:37:08Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalı
dc.description.abstractIntroduction: Vasculitides are a heterogeneous group of disease characterized by inflammation of the blood vessel walls. Etiological factors include infections, drugs, connective tissue diseases, and malignancies.Aim: To examine the demographic characteristics, etiological factors, and treatment options in 75 patients with leukocytoclastic vasculitis.Material and methods: The study included 75 patients diagnosed with leukocytoclastic vasculitis at our clinic. The patients' medical records were reviewed to determine their age, sex, presence of systemic symptoms, possible etiological factors, laboratory results, types of cutaneous lesions, locations of the lesions, treatment options, and disease course.Results: There were 43 women and 32 men. Cutaneous lesions affected only the lower limbs in 60 of the 75 patients (80%) and usually presented as palpable purpura (64%, n = 48). Arthralgia (26.7%, n = 20) was the most frequent extracutaneous symptom. Of the patients with secondary vasculitis, the most common causes were infections and drugs. The mean age of the patients with Henoch-Schonlein purpura was 26.8 years. There was no significant association between age and renal, gastrointestinal, or joint involvement.Conclusions: The most common form of vasculitis in our study was cutaneous leukocytoclastic vasculitis. In most of the patients it appeared to be idiopathic. Among drugs, antibiotics were the most common etiological factor. In 4 patients, the cutaneous leukocytoclastic vasculitis behaved like the paraneoplastic syndrome.
dc.identifier.citationÇakıter, A. Ü., Küçük, Ö. S., Bıyık Özkaya, D., Topukçu, B. ve Onsun, N. (2017). Demographic characteristics, aetiology, and assessment of treatment options in leukocytoclastic vasculitis. Postepy Dermatologii i Alergologii, 34(2), 104-109. https://dx.doi.org/10.5114/ada.2017.67071
dc.identifier.doi10.5114/ada.2017.67071
dc.identifier.endpage109
dc.identifier.issn1642-395X
dc.identifier.issue2
dc.identifier.scopusqualityQ2
dc.identifier.startpage104
dc.identifier.urihttps://dx.doi.org/10.5114/ada.2017.67071
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5478
dc.identifier.volume34
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTermedia Publishing House Ltd.
dc.relation.ispartofPostepy Dermatologii i Alergologiien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLeukocytoclastic Vasculitis
dc.subjectHenoch-Schonlein Purpura
dc.subjectEtiological Factors
dc.titleDemographic characteristics, aetiology, and assessment of treatment options in leukocytoclastic vasculitis
dc.typeArticle

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