Prevalence and clinical profile of patients with myocardial infarction with non-obstructive coronary arteries in Turkey (MINOCA-TR): A national multi-center, observational study

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dc.authorid0000-0003-0205-1138
dc.contributor.authorKılıç, Salih
dc.contributor.authorAydın, Gökhan
dc.contributor.authorÇoner, Ali
dc.contributor.authorKılavuz Doğan, Yasemin
dc.contributor.authorArıcan Özlük, Özlem
dc.contributor.authorÇelik, Yunus
dc.contributor.authorÜnğan, İsmail
dc.contributor.authorTaşcanov, Mustafa
dc.contributor.authorDüz, Ramazan
dc.contributor.authorPolat, Veli
dc.contributor.authorÖzkan, Hakan
dc.contributor.authorÖzyaşar, Mehmet
dc.contributor.authorTülüce, Kamil
dc.contributor.authorKurt, Devrim
dc.contributor.authorÇetin, Nurullah
dc.contributor.authorGül, Murat
dc.contributor.authorİnci, Sinan
dc.contributor.authorYılmaz Coşkun, Fatma
dc.contributor.authorArı, Hasan
dc.contributor.authorZoghi, Megdi
dc.contributor.authorErgene, Oktay
dc.contributor.authorTürk, Uğur Önsel
dc.contributor.authorGök, Gülay
dc.date.accessioned2020-12-18T09:08:04Z
dc.date.available2020-12-18T09:08:04Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractObjective: Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) is a relatively new term that is characterized by clinical evidence of MI with normal or near-normal coronary arteries on coronary angiography (QCA). To date, there have been no population-based studies on the prevalence of MINOCA in Turkey. The aim of this nationwide study was to document the prevalence and demographics of MINOCA in a Turkish population.Methods: MINOCA-TR is national, multi-center, prospective, all-comer study that was conducted in 32 hospitals. All consecutive patients who were >= 18 years old, diagnosed with MI according to the Third Universal Definition of Myocardial Infarction, and had undergone DCA were included in the study. Patients with stable coronary artery disease, unstable angina pectoris, a history of revascularization, and type 4/5 MI were excluded.Results: A total of 1793 patients who were diagnosed with MI and had undergone QCA were screened between March 2018 and October 2018, of whom 1626 (mean age: 61.5 +/- 12.5 years, 70.7% male) were enrolled from 32 centers. The prevalence of MINOCA was 6.7% (n=109) in the overall study population. Compared with non-MINOCA patients, those with MINOCA were younger, had a higher prevalence of the female gender, and had a history of flu. The percentages of current smokers, ST-segment elevated myocardial infarction patients, and those with a history of hypertension, diabetes mellitus, and hyperlipidemia were significantly lower in MINOCA patients (p<0.05, for all). Also, the median left ventricular ejection fraction as seen on echocardiography and the ratio of Killip Class I status at presentation was significantly higher in MINOCA patients than in non-MINOCA patients (p<0.001). Patients with MINOCA received a preload dose of P2Y12 antagonist before QCA less often than non-MINOCA patients (p<0.001).Conclusion: The prevalence of MINOCA in Turkey is 6.7% in patients who were admitted with MI. Also, as compared to non-MINOCA patients, the MINOCA patients were exposed to fewer traditional risk factors of coronary artery disease.
dc.identifier.citationKılıç, S., Aydın, G., Çoner, A., Kılavuz Doğan, Y., Arıcan Özlük, Ö., Çelik, Y. ... Gök, G. (2020). Prevalence and clinical profile of patients with myocardial infarction with non-obstructive coronary arteries in Turkey (MINOCA-TR): A national multi-center, observational study. Anatolian Journal of Cardiology, 23(3), 176-182. https://dx.doi.org/10.14744/AnatolJCardiol.2019.46805
dc.identifier.doi10.14744/AnatolJCardiol.2019.46805
dc.identifier.endpage182
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue3
dc.identifier.scopusqualityQ3
dc.identifier.startpage176
dc.identifier.urihttps://dx.doi.org/10.14744/AnatolJCardiol.2019.46805
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6096
dc.identifier.volume23
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Society of Cardiology
dc.relation.ispartofAnatolian Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMyocardial Infarction With Non-Obstructive Coronary Arteries
dc.subjectMyocardial Infarction
dc.subjectCoronary Angiography
dc.titlePrevalence and clinical profile of patients with myocardial infarction with non-obstructive coronary arteries in Turkey (MINOCA-TR): A national multi-center, observational study
dc.typeArticle

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