Smoking affects global and regional brain entropy in depression patients regardless of depression: preliminary findings

Basit Öğe Kaydı
dc.authorid0000-0002-2306-5937
dc.authorid0000-0003-4292-5717
dc.contributor.authorVelioğlu, Halil Aziz
dc.contributor.authorYıldız, Sultan
dc.contributor.authorÖzdemir Öktem, Ece
dc.contributor.authorÇankaya, Şeyda
dc.contributor.authorLundmark, Anton Kjell
dc.contributor.authorÖzşimşek, Ahmet
dc.contributor.authorHanoğlu, Lütfü
dc.contributor.authorYuluğ, Burak
dc.date.accessioned2024-07-19T07:48:03Z
dc.date.available2024-07-19T07:48:03Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Sinirbilim Ana Bilim Dalı, Doktora Programı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.description.abstractObjective: This study examines the effect of smoking on global and regional brain entropy in patients with Major Depressive Disorder (MDD), aiming to elucidate the relationship between smoking habits and brain network complexity in depression. Methods: The study enrolled 24 MDD patients, divided into smokers and non-smokers, from Alanya Alaaddin Keykubat University and Istanbul Medipol University. Resting-state fMRI data were acquired and processed. The complexity of neuronal activity was assessed using dispersion entropy, with statistical significance determined by a suite of tests including Kolmogorov-Smirnov, Student's t-test, and Mann-Whitney U test. Results: The smoking cohort exhibited higher global brain entropy compared to the non-smoking group (p = 0.033), with significant differences in various brain networks, indicating that smoking may alter global brain activity and network dynamics in individuals with MDD. Conclusion: The study provides evidence that smoking is associated with increased brain entropy in MDD patients, suggesting that chronic smoking may influence cognitive and emotional networks. This underscores the importance of considering smoking history in the treatment and prognosis of MDD. The findings call for further research to understand the mechanistic links between smoking, brain entropy, and depression.
dc.identifier.citationVelioğlu, H. A., Yıldız, S., Özdemir Öktem, E., Çankaya, Ş., Lundmark, A. K., Özşimşek, A. ... Yuluğ, B. (2024). Smoking affects global and regional brain entropy in depression patients regardless of depression: preliminary findings. Journal of Psychiatric Research, 177, 147-152. http://dx.doi.org/10.1016/j.jpsychires.2024.07.002
dc.identifier.doi10.1016/j.jpsychires.2024.07.002
dc.identifier.endpage152
dc.identifier.issn0022-3956
dc.identifier.issn1879-1379
dc.identifier.pmid39018709
dc.identifier.scopus2-s2.0-85198550629
dc.identifier.scopusqualityQ1
dc.identifier.startpage147
dc.identifier.urihttp://dx.doi.org/10.1016/j.jpsychires.2024.07.002
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12734
dc.identifier.volume177
dc.identifier.wos001273201900001en_US
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorVelioğlu, Halil Aziz
dc.institutionauthorYıldız, Sultan
dc.institutionauthorHanoğlu, Lütfü
dc.language.isoen
dc.relation.ispartofJournal of Psychiatric Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBrain Entropy
dc.subjectMajor Depressive Disorder
dc.subjectSmoking
dc.subjectFMRI
dc.titleSmoking affects global and regional brain entropy in depression patients regardless of depression: preliminary findings
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Velioğlu-Halil Aziz-2024.pdf
Boyut:
1.09 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu