Is left ventricular diastolic dysfunction independent from presence of hypertension in metabolic syndrome? An echocardiographic study

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dc.authorid0000-0003-2542-3467
dc.contributor.authorAksoy, Şükrü
dc.contributor.authorDurmuş, Gündüz
dc.contributor.authorÖzcan, Serhan
dc.contributor.authorToprak, Ercan
dc.contributor.authorGürkan, Ufuk
dc.contributor.authorÖz, Dilaver
dc.contributor.authorCanga, Yiğit
dc.contributor.authorKarataş, Baran
dc.contributor.authorDuman, Dursun
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:57:33Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:57:33Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000343527100008
dc.descriptionPubMed ID: 24525047
dc.description.abstractBackground: It has been shown that left ventricular diastolic dysfunction (LVDD) develops in patients with metabolic syndrome (MetS). However, there is not sufficient evidence in the literature to determine whether this condition is due to increase in blood pressure, which is frequently encountered in MetS. The purpose of this study was to test the hypothesis whether LVDD in MetS is independent from the presence of hypertension. Methods: A total of 60 patients diagnosed with MetS and 30 healthy people, who were age- and gender-matched with the patient group, were included in the study as the control group. In the study group, 30 of the patients were normotensive whereas the other 30 had hypertension. Conventional echocardiographic examinations and tissue Doppler imaging were performed besides measurements of demographic and biochemical parameters. Results: In the hypertensive MetS group, early diastolic filling flow (E), early diastolic mitral annular velocity (E'), and E/A ratio were significantly lower compared to the control group. Late diastolic filling flow (A), deceleration time (DT), late diastolic mitral annular velocity (A'), and E/E' ratio were higher in the hypertensive MetS group than the control group. In the normotensive MetS group, E, E', and E/A ratio were also lower compared to the control group whereas DT, A', and E/E' ratio were higher. Conclusion: These findings support the idea that LVDD may develop in patients with MetS even in the absence of hypertension. In addition, co-existence of hypertension with MetS contributes to further worsening of diastolic functions. (C) 2014 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
dc.identifier.citationAksoy, Ş., Durmuş, G., Özcan, S., Toprak, E., Gürkan, U., Öz, D. ... Duman, D. (2014). Is left ventricular diastolic dysfunction independent from presence of hypertension in metabolic syndrome? An echocardiographic study. Journal of Cardiology, 64(3-4), 194-198. https://dx.doi.org/10.1016/j.jjcc.2014.01.002
dc.identifier.doi10.1016/j.jjcc.2014.01.002
dc.identifier.endpage198
dc.identifier.issn0914-5087
dc.identifier.issn1876-4738
dc.identifier.issue45385
dc.identifier.scopusqualityQ2
dc.identifier.startpage194
dc.identifier.urihttps://dx.doi.org/10.1016/j.jjcc.2014.01.002
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3002
dc.identifier.volume64
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofJournal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDiastolic Dysfunction
dc.subjectHypertension
dc.subjectNormotensive
dc.subjectMetabolic Syndrome
dc.titleIs left ventricular diastolic dysfunction independent from presence of hypertension in metabolic syndrome? An echocardiographic study
dc.typeArticle

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