Randomized trial of feasibility and preliminary effectiveness of PerioTabs(R) on periodontal diseases

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dc.authorid0000-0001-6659-8306
dc.contributor.authorAlkan, Begüm
dc.contributor.authorÖzcan, Mutlu
dc.date.accessioned2022-03-18T11:47:45Z
dc.date.available2022-03-18T11:47:45Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Ana Bilim Dalı
dc.description.abstractThis double-blinded and split-mouth design, randomized feasibility study aimed to assess the efficacy of prophylactic and therapeutic use of a new age NitrAdine(TM)-based brushing solution (PerioTabs(R)) on the clinical parameters before and after periodontal therapy. Four subjects were randomly assigned to two treatment groups according to periodontal infection: PerioTabs(R) and placebo. At the first appointment, a split-mouth scaling was performed in all participants. All oral care instructions concerning the use of effervescent tablets were explained to the participants in detail. The morning after the tablets were finished, a full-mouth scaling was completed in all participants. All parameters were recorded at 0, 11, and 40 days. According to the results, both the therapeutic and prophylactic interventions showed similar impacts on the gingival index and probing depth compared to the placebo in all patients. The bleeding on probing was further reduced at the PerioTabs(R) group at baseline until day 40 compared to the placebo in the gingivitis patients with both interventions; at both 11 and 40 days in the periodontitis patients receiving the therapeutic intervention; and at baseline to day 40 in the periodontitis group receiving the prophylactic intervention. While the preliminary results of this new-age brushing solution appear to be a promising approach for a future therapy of periodontal diseases, further research on a larger sample size is needed to draw firm conclusions.
dc.description.sponsorshipBonyf AG, Vaduz, Liechtensteinen_US
dc.identifier.citationAlkan, B. ve Özcan, M. (2022). Randomized trial of feasibility and preliminary effectiveness of PerioTabs(R) on periodontal diseases. Applied Sciences-Basel, 12(3). https://dx.doi.org/10.3390/app12031677
dc.identifier.doi10.3390/app12031677
dc.identifier.issn2076-3417
dc.identifier.issue3
dc.identifier.urihttps://dx.doi.org/10.3390/app12031677
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9141
dc.identifier.volume12
dc.identifier.wos000759132300001en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAlkan, Begüm
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofApplied Sciences-Baselen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAdjunctive Treatment
dc.subjectAntimicrobials
dc.subjectNon-Invasive Treatment
dc.subjectPeriodontology
dc.subjectScaling
dc.subjectRoot Planing
dc.titleRandomized trial of feasibility and preliminary effectiveness of PerioTabs(R) on periodontal diseases
dc.typeArticle

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