The importance of neutrophil/lymphocyte and lymphocyte/monocyte ratios in the diagnosis of influenza in children

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dc.authorid0000-0002-6490-4530
dc.authorid0000-0003-4479-3404
dc.authorid0000-0003-3952-1914
dc.authorid0000-0002-2621-1397
dc.contributor.authorTemel, Hayrettin
dc.contributor.authorGündüz, Mehmet
dc.contributor.authorİstanbullu Tosun, Ayşe
dc.contributor.authorÇelebi, Merve
dc.contributor.authorOkur, Mesut
dc.date.accessioned2021-05-21T11:00:48Z
dc.date.available2021-05-21T11:00:48Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalı
dc.description.abstractBackground: We aimed to analyze the neutrophil/lymphocyte ratio (NLR) and lymphocyte/monocyte ratio (LMR) to investigate their value in supporting the diagnosis of influenza in cases with influenza-like symptoms. Methods: A total of 5,693 pediatric patients who applied to the Pediatric Clinic between January 2015 and Decem-ber 2018 were included in the study. Complete blood count and influenza rapid antigen tests were evaluated at the time of admission. Results: The mean LMR was significantly lower in patients with influenza A than non-influenza A patients (p < 0.001). LMR was also significantly lower in those with influenza A or B compared to those in the influenza-nega-tive group (p < 0.001). There was no significant difference (p = 0.83) in terms of the mean LMR between influenza B positive and negative patients. The mean NLR was significantly higher in influenza A positive patients in com-parison with influenza A negative patients (p < 0.001), and it was significantly lower in influenza B positive pa-tients than in influenza B negative patients (p < 0.001). Conclusions: We concluded that LMR and NLR, which had been rarely examined in the literature, had important value in the diagnosis of influenza. However, these values alone were far from being sufficient for the definitive di-agnosis of influenza.
dc.identifier.citationTemel, H., Gündüz, M., İstanbullu Tosun, A., Çelebi, M. ve Okur, M. (2021). The importance of neutrophil/lymphocyte and lymphocyte/monocyte ratios in the diagnosis of influenza in children. Clinical Laboratory, 67(4), 1073-1078. https://dx.doi.org/10.7754/Clin.Lab.2020.200907
dc.identifier.doi10.7754/Clin.Lab.2020.200907
dc.identifier.endpage1078
dc.identifier.issn1433-6510
dc.identifier.issue4
dc.identifier.scopusqualityQ3
dc.identifier.startpage1073
dc.identifier.urihttps://dx.doi.org/10.7754/Clin.Lab.2020.200907
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6880
dc.identifier.volume67
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerlag Klinisches Labor GmbH
dc.relation.ispartofClinical Laboratoryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChild
dc.subjectInfluenza
dc.subjectLymphocyte / Monocyte
dc.subjectNeutrophil / Lymphocyte
dc.titleThe importance of neutrophil/lymphocyte and lymphocyte/monocyte ratios in the diagnosis of influenza in children
dc.typeArticle

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