Microbial analysis of endodontic infections in teeth with post-treatment apical periodontitis before and after medication

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dc.authorid0000-0002-0354-5108
dc.authorid0000-0003-1844-1288
dc.contributor.authorErşahan, Şeyda
dc.contributor.authorErdem Hepşenoğlu, Yelda
dc.date.accessioned2023-09-19T11:28:00Z
dc.date.available2023-09-19T11:28:00Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Endodonti Ana Bilim Dalı
dc.description.abstractThis study aimed to determine the intraradicular microbiota of previously root canal-treated teeth with apical periodontitis and to investigate the antibacterial effectiveness of different intracanal medicaments. Sixteen patients with post-treatment apical periodontitis were allocated into two groups according to the intracanal medicament used: calcium hydroxide (CH) and 2% chlorhexidine gluconate gel (CHX) group. Total bacterial loads, as well as the amount of Enterococcus faecalis (E. faecalis) were determined before (S1) and after (S2) chemomechanical preparation and finally, after intracanal medication (S3) by means of ddPCR. The unpaired t test was used to compare parametric. S3-total bacteria copy number of the CH group was lower than the CHX group (p < 0.05). There was no statistical difference between the CHX- and the CH groups in terms of E.faecalis copy number (p > 0.05). But in terms of total bacteria, CH is better than CHX. Consequently, CH can be used to optimise the antibacterial efficiency of chemomechanical preparation in previously root canal-treated teeth with apical periodontitis.
dc.description.sponsorshipIstanbul Medipol Universityen_US
dc.identifier.citationErşahan, Ş. ve Erdem Hepşenoğlu, Y. (2023). Microbial analysis of endodontic infections in teeth with post-treatment apical periodontitis before and after medication. Australian Endodontic Journal, 49(1), 75-86. https://doi.org/10.1111/aej.12613
dc.identifier.doi10.1111/aej.12613
dc.identifier.endpage86
dc.identifier.issn1329-1947
dc.identifier.issn1747-4477
dc.identifier.issue1
dc.identifier.pmid35239214
dc.identifier.scopus2-s2.0-85125517578
dc.identifier.scopusqualityQ1
dc.identifier.startpage75
dc.identifier.urihttps://doi.org/10.1111/aej.12613
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11459
dc.identifier.volume49
dc.identifier.wos000763555000001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErşahan, Şeyda
dc.institutionauthorErdem Hepşenoğlu, Yelda
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofAustralian Endodontic Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectChemomechanical Preparation
dc.subjectDroplet Digital
dc.subjectEnterococcus Faecalis
dc.subjectIntracanal Medicaments
dc.subjectMicrobiology
dc.subjectPost-Treatment Apical Periodontitis
dc.subjectTotal Bacterial Load
dc.titleMicrobial analysis of endodontic infections in teeth with post-treatment apical periodontitis before and after medication
dc.typeArticle

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