Effect of oral use of various edible oils on wound healing in rats: Randomized controlled experimental study

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dc.authorid0000-0001-7933-4262
dc.authorid0000-0002-7059-1884
dc.authorid0000-0003-1420-0989
dc.contributor.authorÇakmak Kafadar, Gökçe
dc.contributor.authorBüyükuslu, Nihal
dc.contributor.authorKolbaşı, Bircan
dc.contributor.authorKeskin, İlknur
dc.contributor.authorMercan, Yeliz
dc.date.accessioned2022-06-06T08:54:28Z
dc.date.available2022-06-06T08:54:28Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Beslenme ve Diyetetik Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractThere are various studies showing that oral supplements are shortening or facilitat-ing effects on this process. Therefore, this study investigates the use of edible oils as supplements in the wound healing process. Of the 7 groups (control, Hypericum perforatum extracts in olive oil, olive, sesame, fish, black seed, sunflower), each has 8 Wistar Albino rats. In the experimental groups, 1.25 mL/kg oral oil was used for 10 days. Macroscopic images of the wound area were taken. Wound healing was evaluated by histological analysis. Collagen III, IL-6, TNF-? and TGF-ß1 density analyzes were performed on the tissue samples. According to macroscopic analysis, wound narrowing is higher in all groups on the 2nd and 4th days than the control group. Histopathological and immunohistochemical analyses of all experimental groups except sunflower oil group revealed better results than control group.
dc.identifier.citationÇakmak Kafadar, G., Büyükuslu, N., Kolbaşı, B., Keskin, İ. ve Mercan, Y. (2022). Effect of oral use of various edible oils on wound healing in rats: Randomized controlled experimental study. Acta Pharmaceutica Sciencia, 60(2), 179-201. https://doi.org/10.23893/1307-2080.APS.6013
dc.identifier.doi10.23893/1307-2080.APS.6013
dc.identifier.endpage201
dc.identifier.issn1307-2080
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85130220102
dc.identifier.scopusqualityQ3
dc.identifier.startpage179
dc.identifier.urihttps://doi.org/10.23893/1307-2080.APS.6013
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9506
dc.identifier.volume60
dc.indekslendigikaynakScopus
dc.institutionauthorBüyükuslu, Nihal
dc.institutionauthorKolbaşı, Bircan
dc.institutionauthorKeskin, İlknur
dc.language.isoen
dc.publisherIstanbul Medipol University
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectBlack Cumin Oil
dc.subjectHypericum Perforatum Olive Oil Extract
dc.subjectOlive Oil
dc.subjectSesame Oil
dc.subjectSunflower Oil
dc.subjectWound Healing
dc.titleEffect of oral use of various edible oils on wound healing in rats: Randomized controlled experimental study
dc.typeArticle

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