Is thymus size at birth associated with respiratory distress syndrome in preterm infants?

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dc.authorid0000-0003-1735-4318
dc.contributor.authorYılmaz-Semerci, Seda
dc.contributor.authorDemirel, Gamze
dc.contributor.authorBaşkan, Özdil
dc.contributor.authorTaştekin, Ayhan
dc.date.accessioned2020-09-18T10:41:10Z
dc.date.available2020-09-18T10:41:10Z
dc.date.issued2019
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.description.abstractAIM: Thymus size in neonates depend on many factors. We aimed to assess the thymus size radiographically in preterm neonates and its relationship with respiratory distress syndrome (RDS) and other complications of prematurity. METHODS: Thymus size was assessed by cardiothymic: thoracic ratio (CT/T), measuring the width of the cardiothymic shadow at the level of carina and dividing it by the width of the thorax at the costophrenic angles, from the first chest radiograph in patients less than 34 weeks gestational age. RESULTS: Neonates born between 30-34 weeks of gestation with RDS had smaller CT/T than non RDS group (0.34±0.1 vs 0.36±0.05, p=0.045). Birth weight has positive correlation with CT/T (r=0.166, p=0.03). CONCLUSION: Thymus involution in the perinatal period is a complex process and the response is variable in different clinical situations. Activated hypothalamic-pituitary-adrenal (HPA) axis may be responsible for thymic involution in preterm infants between 30-34 weeks of gestation with RDS.
dc.identifier.citationYılmaz-Semerci, S., Demirel, G., Başkan, Ö. ve Taştekin, A. (2019). Is thymus size at birth associated with respiratory distress syndrome in preterm infants? Journal of Neonatal-Perinatal Medicine, 12(3), 345-349. https://dx.doi.org/10.3233/NPM-180066
dc.identifier.doi10.3233/NPM-180066
dc.identifier.endpage349
dc.identifier.issn1934-5798
dc.identifier.issue3
dc.identifier.scopusqualityQ3
dc.identifier.startpage345
dc.identifier.urihttps://dx.doi.org/10.3233/NPM-180066
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5865
dc.identifier.volume12
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherIOS Press
dc.relation.ispartofJournal of Neonatal-Perinatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCardiothymic/Thoracic Ratio
dc.subjectPreterm Infants
dc.subjectRespiratory Distress Syndrome
dc.subjectThymus Size
dc.titleIs thymus size at birth associated with respiratory distress syndrome in preterm infants?
dc.typeArticle

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