Health-related quality of life in patients with bronchiolitis obliterans

Basit Öğe Kaydı
dc.authorid0000-0003-3105-0409
dc.authorid0000-0002-7950-2067
dc.contributor.authorAtağ, Emine
dc.contributor.authorBaş İkizoğlu, Nilay
dc.contributor.authorErgenekon, Pınar
dc.contributor.authorKalın, Sevinç
dc.contributor.authorÜnal, Füsun
dc.contributor.authorGökdemir, Yasemin
dc.contributor.authorErdem Eralp, Ela
dc.contributor.authorYalçın, Koray
dc.contributor.authorÖktem, Sedat
dc.contributor.authorErsu, Refika
dc.contributor.authorKarakoç, Fazilet
dc.contributor.authorKaradağ, Bülent
dc.date.accessioned2020-10-21T11:59:01Z
dc.date.available2020-10-21T11:59:01Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractIntroduction Bronchiolitis obliterans (BO) is mainly caused by infections and hematopoietic stem cell transplantation (HSCT). This study aimed to investigate the health-related quality of life (HRQOL) of children with BO compared to the healthy children and also to assess the HRQOL according to the etiology. Methods Postinfectious (group 1) and post-HSCT BO (group 2) patients and healthy children were included in the study. HRQOL was assessed by the Short Form-36 (SF-36) and St George's Respiratory Questionnaire (SGRQ). Correlations between demographic and clinical characteristics, pulmonary function tests, high-resolution chest tomography scores, and HRQOL were assessed. Results Thirty-seven postinfectious and post-HSCT BO patients and 34 healthy children were included in the study. Mean age was 13.8 +/- 0.7 years. Mean forced vital capacity and forced expiratory volume(1)were 60.7 +/- 2.7% predicted, and 49.8 +/- 3.1% predicted, respectively. The SF-36 scores were lower in BO patients compared to healthy children (P < .01). Patients with better lung functions had higher SF-36 scores, but lower SGRQ. The number of inhaled therapies, acute exacerbations, hospitalizations were inversely correlated with SF-36. A positive correlation was found between these parameters and total SGRQ scores (r = .507,P = .02;r = .409,P = .12;r = .326,P = .049, respectively). SF-36 scores were better in group 1 for subscales of physical role functioning and social role functioning compared to group 2. (P = .01,P = .01, respectively). Conclusion The HRQOL of patients with BO measured by SF-36 was low compared to healthy children. SF-36 scores were more affected in post-HSCT BO patients. HRQOL of children with chronic lung disease should be taken into consideration in the management of these patients.
dc.identifier.citationAtağ, E., Baş İkizoğlu, N., Ergenekon, P., Kalın, S., Ünal, F., Gökdemir, Y. ... Karadağ, B. (2020). Health-related quality of life in patients with bronchiolitis obliterans. Pediatric Pulmonology, 55(9), 2361-2367. https://dx.doi.org/10.1002/ppul.24896
dc.identifier.doi10.1002/ppul.24896
dc.identifier.endpage2367
dc.identifier.issn8755-6863
dc.identifier.issn1099-0496
dc.identifier.issue9
dc.identifier.scopusqualityQ1
dc.identifier.startpage2361
dc.identifier.urihttps://dx.doi.org/10.1002/ppul.24896
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5956
dc.identifier.volume55
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofPediatric Pulmonologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectBronchiolitis Obliterans
dc.subjectChildren
dc.subjectQuality of Life
dc.titleHealth-related quality of life in patients with bronchiolitis obliterans
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
Atag, Emine-2020.pdf
Boyut:
622.4 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu