Contribution of dual fluorescein and indocyanine green angiography to the appraisal of posterior involvement in birdshot retinochoroiditis and Vogt-Koyanagi-Harada disease

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dc.authorid0000-0001-6090-4448
dc.contributor.authorBalcı, Özlem
dc.contributor.authorJeannin, Bruno
dc.contributor.authorHerbort, Carl Peter
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:50:45Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:50:45Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000431304900013
dc.descriptionPubMed ID: 28299496
dc.description.abstractPurpose To assess the levels of retinal and choroidal involvement in initial-onset birdshot retinochoroiditis (BRC) and Vogt-Koyanagi-Harada (VKH) disease, two stromal choroiditis entities. Methods This retrospective study included patients diagnosed with BRC and VKH, seen during initialonset disease at the Centre for Ophthalmic Specialized Care, Lausanne, Switzerland. Angiographic signs were quantified, using an established dual fluorescein angiography (FA) and indocyanine green angiography (ICGA) scoring system for uveitis, and the FA/ICGA score ratios were compared between diseases. Results Among 1793 patients with uveitis seen from 1995 to 2015, 7 newly diagnosed BRC patients and 4 patients with newly diagnosed VKH disease had sufficient data for study inclusion. Patients with BRC and VKH at initial onset had mean FA angiographic scores of 16.91 +/- 3.42 and 4.06 +/- 1.87; mean ICGA angiographic scores of 21.34 +/- 3.49 and 25.75 +/- 3.88; and mean FA/ICGA ratios of 0.79 +/- 0.21 and 0.16 +/- 0.09, respectively. Conclusion This study showed the differential involvements of the retina and choroid in BRC and VKH. The choroid was preponderantly involved in both diseases; thus, ICGA is essential for disease assessment and follow-up. However, these diseases also differed substantially. The origin of inflammation was primarily in the choroid in VKH and in both the choroid and retina in BRC. We recommend dual FA and ICGA for evaluating posterior uveitis, when choroiditis is suspected.
dc.identifier.citationBalcı, Ö., Jeannin, B. ve Herbort, C. P. (2018). Contribution of dual fluorescein and indocyanine green angiography to the appraisal of posterior involvement in birdshot retinochoroiditis and Vogt-Koyanagi-Harada disease. International Ophthalmology, 38(2), 527-539. https://dx.doi.org/10.1007/s10792-017-0487-5
dc.identifier.doi10.1007/s10792-017-0487-5
dc.identifier.endpage539
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue2
dc.identifier.scopusqualityQ2
dc.identifier.startpage527
dc.identifier.urihttps://dx.doi.org/10.1007/s10792-017-0487-5
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2064
dc.identifier.volume38
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Netherlands
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectBirdshot Retinochoroiditis
dc.subjectVogt-Koyanagi-Harada Disease
dc.subjectIndocyanine Green Angiography
dc.subjectFluorescein Angiography
dc.subjectAngiographic Score
dc.titleContribution of dual fluorescein and indocyanine green angiography to the appraisal of posterior involvement in birdshot retinochoroiditis and Vogt-Koyanagi-Harada disease
dc.typeArticle

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