Relation of metabolic syndrome with endometrial pathologies in patients with abnormal uterine bleeding

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dc.contributor.authorÖzdemir, Suna
dc.contributor.authorBatmaz, Gonca
dc.contributor.authorAteş, Seda
dc.contributor.authorÇeli?k, Çetin
dc.contributor.authorİncesu, Feyzanur
dc.contributor.authorPeru, Celalettin
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:56:08Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:56:08Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.descriptionWOS: 000369949900011
dc.descriptionPubMed ID: 26182187
dc.description.abstractPurpose: We aimed to investigate the association of metabolic syndrome and metabolic risk factors with endometrial hyperplasia and carcinoma among women with abnormal uterine bleeding (AUB). Methods: This study included 199 patients who had undergone endometrial curettage due to abnormal uterine bleeding. We divided the patients into two groups according to whether they had an abnormal (n = 53) or normal endometrium (n = 146). Waist circumference, blood pressure, fasting glucose and serum lipid levels were measured and statistically analyzed. The women in each group were matched with regard to mean age, gravidity, parity and menopausal status. Results: We found increased prevalence of metabolic syndrome, diabetes, general and abdominal obesity, hypertension, elevated levels of glucose, total cholesterol and LDL-cholesterol and reduced levels of HDL-cholesterol among women with endometrial carcinoma and hyperplasia. These results were detected particularly in postmenopausal (450 years) women compared to pre-menopausal cases (550 years). All metabolic parameters were similar between hyperplasia and cancer groups. Conclusion: Metabolic syndrome and its components have been shown to have profound impacts on initiation and progession of endometrial pathology, particularly during postmenopausal period.
dc.identifier.citationÖzdemir, S., Batmaz, G., Ateş, S., Çeli?k, Ç., İncesu, F. ve Peru, C. (2015). Relation of metabolic syndrome with endometrial pathologies in patients with abnormal uterine bleeding. Gynecological Endocrinology, 31(9), 725-729. https://dx.doi.org/10.3109/09513590.2015.1058355
dc.identifier.doi10.3109/09513590.2015.1058355
dc.identifier.endpage729
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue9
dc.identifier.scopusqualityQ2
dc.identifier.startpage725
dc.identifier.urihttps://dx.doi.org/10.3109/09513590.2015.1058355
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2591
dc.identifier.volume31
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor and Francis
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEndometrium
dc.subjectMetabolic Syndrome
dc.subjectPathology
dc.subjectUterine Bleeding
dc.titleRelation of metabolic syndrome with endometrial pathologies in patients with abnormal uterine bleeding
dc.typeArticle

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