The effects of cigarette smoking on the Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio

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dc.contributor.authorİlgenli, Tevfik Fikret
dc.contributor.authorTokatlı, Alptu?
dc.contributor.authorAkpınar, Onur
dc.contributor.authorKılıçaslan, Fethi
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:47Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:47Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractBackground. Cigarette smoking increases the risk of sudden cardiac death. Smoking may predispose individuals to ventricular fibrillation and sudden cardiac death by altering ventricular repolarization and stimulating sympathetic nervous system activity. Objectives. The aim of the study was to investigate the instantaneous effects of smoking on ventricular repolarization. Material and Methods. The study included 47 healthy subjects; 24 long-term heavy smokers (10 women, mean age: 40 ± 5 years) constituted the study group, and 23 non-smokers (10 women, mean age: 42 ± 10 years) constituted the control group. ECGs were performed on all the subjects. The Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio were measured and compared between the groups. Results. There were no significant differences between smokers and nonsmokers in the basic clinical and echocardiographic variables (p > 0.05). The QT interval and QTc interval were similar in both groups. The Tp-e interval (p = 0.02) and Tpe/QT ratio (p = 0.001) were higher in the heavy smokers than in the non-smokers. The Tpe/QTc ratio (p = 0.001) was also higher in the smokers. Other ECG parameters were similar between the smokers and nonsmokers. Conclusions. The results show that chronic cigarette smoking is associated with a prolonged Tp-e interval, increased Tp-e/QT ratio and Tp-e/QTc ratio. These observations may indicate that there may be a relationship between smoking and altered ventricular repolarization. Abnormal ventricular repolarization values on an ECG may explain the increased cardiovascular event risk in long-term heavy cigarette smokers.
dc.identifier.citationİlgenli, T. F., Tokatlı, A., Akpınar, O. ve Kılıçaslan, F. (2015). The effects of cigarette smoking on the Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio. Advances in Clinical and Experimental Medicine, 24(6), 973-978. https://dx.doi.org/10.17219/acem/28114
dc.identifier.doi10.17219/acem/28114
dc.identifier.endpage978
dc.identifier.issn1899-5276
dc.identifier.issue6
dc.identifier.scopusqualityQ2
dc.identifier.startpage973
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1254
dc.identifier.urihttps://dx.doi.org/10.17219/acem/28114
dc.identifier.volume24
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWroclaw University of Medicine
dc.relation.ispartofAdvances in Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSmoking
dc.subjectTp-e Interval
dc.subjectTp-e/QT Ratio
dc.subjectTp-e/QTc Ratio
dc.titleThe effects of cigarette smoking on the Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio
dc.typeArticle

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