High flow nasal cannula versus nasal continuous positive airway pressure for primary respiratory support in preterm infants: A prospective randomized study

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dc.authorid0000-0003-1735-4318
dc.contributor.authorDemirel, Gamze
dc.contributor.authorVatansever, Binay
dc.contributor.authorTaştekin, Ayhan
dc.date.accessioned2020-03-23T10:22:59Z
dc.date.available2020-03-23T10:22:59Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective b-This study compares high flow nasal cannula (HFNC) with nasal continuous positive airway pressure (nCPAP) within the first hour of life as the primary respiratory support in neonates of ?32 weeks of gestational age. Study Design b-This prospective, randomized study was conducted in infants with a gestational age of ?32 weeks who had spontaneous respiration. HFNC or nCPAP was used as a first line respiratory support after admission to intensive care unit. Primary outcome was primary treatment failure. Secondary outcomes were duration of noninvasive respiratory support and oxygen treatment, maximum FiO 2level, length of hospital stay, intubation rate, rates of respiratory distress syndrome, pneumothorax, and bronchopulmonary dysplasia. Subgroup analysis was performed for infants ?28 weeks of gestational age. Results b-We enrolled 107 infants, 53 in HFNC and 54 to nCPAP group. There was no difference in primary outcome between the two groups. There was no difference between the groups in aspect of secondary outcomes. Conclusion b-HFNC and nCPAP have no significant differences as a primary mode of respiratory support in preterm infants, in the time to wean off the devices and oxygen support, respiratory distress syndrome and bronchopulmonary dysplasia incidence, hospitalization duration, and rates of complications of prematurity.
dc.identifier.citationDemirel, G., Vatansever, B. ve Taştekin, A. (2021). High flow nasal cannula versus nasal continuous positive airway pressure for primary respiratory support in preterm infants: A prospective randomized study. American Journal of Perinatology, 38(3), 237-241. http://doi.org/10.1055/s-0039-1696673
dc.identifier.doi10.1055/s-0039-1696673
dc.identifier.endpage241
dc.identifier.issn0735-1631
dc.identifier.issn1098-8785
dc.identifier.issue3
dc.identifier.scopusqualityQ1
dc.identifier.startpage237
dc.identifier.urihttp://doi.org/10.1055/s-0039-1696673
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5072
dc.identifier.volume38
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherThieme Medical Publishers, Inc.
dc.relation.ispartofAmerican Journal of Perinatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectHigh Flow Nasal Cannula
dc.subjectNasal Continuous Positive Airway Pressure
dc.subjectPreterm Infan
dc.subjectRespiratory Distress
dc.titleHigh flow nasal cannula versus nasal continuous positive airway pressure for primary respiratory support in preterm infants: A prospective randomized study
dc.typeArticle

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