Paradoxic relations between basilar artery reconfiguration and superior cervical ganglia ischemia after bilateral common carotid artery ligation
| dc.contributor.author | Kılıç, Mustafa | |
| dc.contributor.author | Kılıç, Betül Aydın | |
| dc.contributor.author | Aydın, Mehmet Dumlu | |
| dc.contributor.author | Kanat, Ayhan | |
| dc.contributor.author | Yılmaz, İlhan | |
| dc.contributor.author | Eşeoğlu, Metehan | |
| dc.contributor.author | Gündoğdu, Betül | |
| dc.date.accessioned | 2019-12-24T14:07:44Z | |
| dc.date.available | 2019-12-24T14:07:44Z | |
| dc.date.issued | 2019 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı | |
| dc.description.abstract | Background: The relationship between superior cervical ganglia (SCG) ischemia due to bilateral common carotid artery ligation (BCCAL) and basilar artery (BA) reconfiguration was investigated. Methods: Twenty-three rabbits were randomly divided into 3 groups: group III rabbits underwent BCCAL (n = 13), group II rabbits were sham-operated controls (n = 5), and group I rabbits did not undergo surgery (n = 5). Degenerated neuron densities (DND) within the SCG were correlated with the BA vasodilatation index (VDI). Results: Mean live and DND in SCG of group I rabbits were 11.235 ± 982/?m3 and 11 ± 3/?m3, respectively, with a mean heart rate of 294 ± 21 beats/min. Mean SCG DND and heart rates were 213 ± 42/?m3 and 242 ± 17 beats/min for the sham group (group II) rabbits and 1743 ± 285/?m3 and 199 ± 19 beats/min for the study group (group III) rabbits, respectively. The BA VDI values in the sham group (group II) (1.32 ± 0.10) and the study group (group III) (0.976 ± 0.112) significantly differed from those in the control group (group I) (1.65 ± 0.12; P < 0.005) versus the sham group (group II) (P < 0.0001) versus the BCCAL applied group (group III) and between group II and group III (P < 0.005). Conclusions: A meaningful and paradoxic correlation was detected between the BA VDI values and degenerated neuron density of SCG after BCCAL. Although a low degenerated neuron density within SCG may provoke excessive sympathetic activity and prevent excessive BA dilatation with steno-occlusive carotid artery diseases, a high degenerated neuron density may cause dangerous vasodilatation of BA. | |
| dc.identifier.citation | Kılıç, M., Kılıç, B. A., Aydın, M. D., Kanat, A., Yılmaz, İ., Eşeo?lu, M. ve Gündo?du, B. (2019). Paradoxic relations between basilar artery reconfiguration and superior cervical ganglia ischemia after bilateral common carotid artery ligation. World Neurosurgery, 125, e658-e664. http://doi.org/10.1016/j.wneu.2019.01.144. | |
| dc.identifier.doi | 10.1016/j.wneu.2019.01.144 | |
| dc.identifier.endpage | e664 | |
| dc.identifier.issn | 18788750 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | e658 | |
| dc.identifier.uri | http://doi.org/10.1016/j.wneu.2019.01.144 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/4661 | |
| dc.identifier.volume | 125 | |
| dc.identifier.wosquality | Q3 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Elsevier | |
| dc.relation.ispartof | World Neurosurgery | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Basilar Artery Vasodilatation | |
| dc.subject | Common Carotid Artery Ligation | |
| dc.subject | Degenerated Neuron Density | |
| dc.subject | Superior Cervical Ganglion | |
| dc.title | Paradoxic relations between basilar artery reconfiguration and superior cervical ganglia ischemia after bilateral common carotid artery ligation | |
| dc.type | Article |
