How to create an experimental diabetes mellitus model?

dc.authorid0000-0003-0052-3648
dc.contributor.authorParlar Köprülü, Rabia Edibe
dc.date.accessioned2023-04-26T08:27:45Z
dc.date.available2023-04-26T08:27:45Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Tıbbi Farmakoloji Ana Bilim Dalı
dc.description.abstractDiabetes is a metabolic disorder characterized by chronic hyperglycemia. Early treatment is very important in terms of preventing diabetes-related late complications with high treatment costs and increasing the patient’s quality of life. In addition to investigating the pathophysiology of the disease studied, animal experiments pave the way for new approaches in treatments. Although there are many methods that can be used when creating a diabetes model, induction of diabetes with alloxan and streptozotocin are the most preferred ones. The aim of this article is to review the available information on diabetes-related methods, common problems and solutions, with known mechanisms of action, dose and time-determined methods.
dc.identifier.citationParlar Köprülü, R. E. (2023). How to create an experimental diabetes mellitus model? Pharmacia, 70(1), 105-111. https://dx.doi.org/10.3897/pharmacia.70.e96028
dc.identifier.doi10.3897/pharmacia.70.e96028
dc.identifier.endpage111
dc.identifier.issn0428-0296
dc.identifier.issn2603-557X
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85152140295
dc.identifier.scopusqualityQ3
dc.identifier.startpage105
dc.identifier.urihttps://dx.doi.org/10.3897/pharmacia.70.e96028
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10894
dc.identifier.volume70
dc.identifier.wos001001035500001en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorParlar Köprülü, Rabia Edibe
dc.language.isoen
dc.publisherPensoft Publishers
dc.relation.ispartofPharmaciaen_US
dc.relation.publicationcategoryDiğer
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectExperimental Diabetes
dc.subjectMethod
dc.subjectStreptozocin
dc.subjectAlloxan
dc.titleHow to create an experimental diabetes mellitus model?
dc.typeReview Article

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