In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism

dc.authorid0000-0003-0205-1138
dc.authorid0000-0003-2542-3467
dc.contributor.authorGök, Gülay
dc.contributor.authorKaradağ, Mehmet
dc.contributor.authorÇınar, Tufan
dc.contributor.authorNurkalem, Zekeriya
dc.contributor.authorDuman, Dursun
dc.date.accessioned2021-01-07T08:46:27Z
dc.date.available2021-01-07T08:46:27Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractIntroduction: The aim of this study was to evaluate the in-hospital and short-term predictive factors of mortality in intermediate-high risk acute pulmonary embolism (PE) patients with right ventricle (RV) dysfunction and myocardial injury.Methods: In this retrospective study, the medical records of 187 patients with a diagnosis of intermediatehigh risk acute PE were evaluated. A contrast-enhanced multi-detector pulmonary angiography was used to confirm diagnosis in all cases. All-cause mortality was determined by obtaining both in-hospital and 30 days follow-up data of patients from medical records.Results: During the in-hospital stay (9.5 +/- 4.72 days), 7 patients died, resulting in an acute PE related in-hospital mortality of 3.2%. Admission heart rate (HR), (Odds ratio (OR), 1.028 95% Confidence interval (CI), 0.002-1.121; P = 0.048) and blood urea nitrogen (BUN) (OR, 1.028 95% CI, 0.002-1.016; P = 0.044) were found to be independent predictors for in-hospital mortality in a multivariate logistic regression analysis. In total, 32 patients (20.9%) died during 30 days follow-up.The presence of congestive heart failure (OR, 0.015, 95%CI, 0.001-0.211; P = 0.002) and dementia (OR, 0.029, 95%CI, 0.002-0.516; P = 0.016) as well as low albumin level (OR, 0.049 95%CI, 0.006-0.383; P = 0.049) were associated with 30 days mortality.Conclusion: HR and BUN were independent predictors of in-hospital mortality and the presence of congestive heart failure, dementia, and low albumin levels were associated with higher 30 days mortality.
dc.identifier.citationGök, G., Karadağ, M., Çınar, T., Nurkalem, Z. ve Duman, D. (2020). In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism. Journal of Cardiovascular and Thoracic Research, 12(4), 321-327. https://dx.doi.org/10.34172/jcvtr.2020.51
dc.identifier.doi10.34172/jcvtr.2020.51
dc.identifier.endpage327
dc.identifier.issn2008-5117
dc.identifier.issn2008-6830
dc.identifier.issue4
dc.identifier.scopusqualityN/A
dc.identifier.startpage321
dc.identifier.urihttps://dx.doi.org/10.34172/jcvtr.2020.51
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6197
dc.identifier.volume12
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTabriz University of Medical Sciences and Health Services
dc.relation.ispartofJournal of Cardiovascular and Thoracic Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAcute Pulmonary Embolism
dc.subjectMortality
dc.subjectIntermediate-High Risk
dc.titleIn-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism
dc.typeArticle

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