Respiratory syncytial virus infections in pediatric intensive care: association of sociodemographic data and clinical outcomes with viral and bacterial co-infections
| dc.contributor.author | Koçoğlu Barlas, Ülkem | |
| dc.contributor.author | Akçay, Nihal | |
| dc.contributor.author | Telhan, Leyla | |
| dc.contributor.author | Kanğın, Murat | |
| dc.contributor.author | Umur, Özge | |
| dc.contributor.author | Çıtak, Agop | |
| dc.contributor.author | Boydağ Güvenç, Kübra | |
| dc.date.accessioned | 2025-06-12T06:59:17Z | |
| dc.date.available | 2025-06-12T06:59:17Z | |
| dc.date.issued | 2024 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | |
| dc.description.abstract | Objective: The aim of the study was to evaluate respiratory syncytial virus (RSV) infections in cases followed in the pediatric intensive care unit (PICU). Materials and Methods: The study was designed as a prospective cohort in 6 PICUs. There were 3 groups: only RSV (+), RSV (v+) who were positive for another viral agent(s) in addition to RSV, and RSV (b+) who were positive for a bacterial agent(s) in addition to RSV. Results: A total of 119 cases were included in the study, 67 (56.3%) of whom were male. The RSV (+) group had a lower pH compared to the other groups and a higher rate of acute bronc hiolitis/bronchitis diagnoses compared to the RSV (v+) group. The RSV (v+) group had higher bicarbonate levels, higher creatinine levels, longer hospital stays, and higher Pediatric Risk of Mortality-3 scores (PRISM-3) compared to the RSV (+) group. Cases with RSV (b+) were younger and also had lower body weight compared to the other groups. Furthermore, the RSV (b+) group had higher C-reactive protein and Procalcitonin (PCT) levels and higher rates of High Flow Nasal Cannula-Oxygen Therapy (HFNC-OT) use. Multiple linear regression analysis revealed that PRISM-3 score, PCT levels, Pediatric Acute Respiratory Distress Syndrome diagnoses, inhaled steroid use, chronic illness status, and heart rate on admission were associated with the length of stay in the PICU. Conclusion:High flow nasal cannula-oxygen therapy continues to be the most frequently preferred respiratory support method in RSV infections. Viral infections accompanying RSV can increase the severity of the disease. | |
| dc.identifier.citation | Koçoğlu Barlas, Ü., Akçay, N., Telhan, L., Kanğın, M., Umur, Ö., Çıtak, A. ... Boydağ Güvenç, K. (2024). Respiratory syncytial virus infections in pediatric intensive care: association of sociodemographic data and clinical outcomes with viral and bacterial co-infections. Turkish Archives of Pediatrics, 59(5), 494-500. http://dx.doi.org/10.5152/TurkArchPediatr.2024.24149 | |
| dc.identifier.doi | 10.5152/TurkArchPediatr.2024.24149 | |
| dc.identifier.endpage | 500 | |
| dc.identifier.issn | 2757-6256 | |
| dc.identifier.issue | 5 | |
| dc.identifier.pmid | 39440440 | |
| dc.identifier.scopus | 2-s2.0-85203714270 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 494 | |
| dc.identifier.uri | http://dx.doi.org/10.5152/TurkArchPediatr.2024.24149 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/12951 | |
| dc.identifier.volume | 59 | |
| dc.identifier.wos | WOS:001352409400011 | |
| dc.identifier.wosquality | Q3 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.institutionauthor | Telhan, Leyla | |
| dc.institutionauthor | Kanğın, Murat | |
| dc.institutionauthorid | 0000-0003-0037-7636 | |
| dc.institutionauthorid | 0000-0003-0042-0569 | |
| dc.language.iso | en | |
| dc.relation.ispartof | Turkish Archives of Pediatrics | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights | Attribution-NonCommercial 4.0 International | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
| dc.subject | Co-Infections | |
| dc.subject | Intensive Care | |
| dc.subject | Pediatric | |
| dc.subject | Respiratory Syncytial Virus | |
| dc.title | Respiratory syncytial virus infections in pediatric intensive care: association of sociodemographic data and clinical outcomes with viral and bacterial co-infections | |
| dc.type | Article |
